Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression (Q39824870)

15 September 2017

Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression (English)

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15 September 2017

Fabio Carrozzino

1

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15 September 2017

Paolo Pugnale

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2

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15 September 2017

Eric Féraille

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3

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15 September 2017

Roberto Montesano

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4

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15 September 2017

15 July 2009

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American Journal of Physiology - Cell Physiology

15 September 2017

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15 September 2017

297

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15 September 2017

3

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15 September 2017

C775-87

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Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cells

15 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Renal localization and function of the tight junction protein, claudin-19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Role of p38 MAP kinase and transforming growth factor-beta signaling in transepithelial migration of invasive bacterial pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Differential expression of claudin 1, 3, and 4 during normal mammary gland development in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Growth defects induced by perturbation of beta1-integrin function in the mammary gland epithelium result from a lack of MAPK activation via the Shc and Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Role for TGF-beta in cyclosporine-induced modulation of renal epithelial barrier function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Impaired tight junction sealing and precocious involution in mammary glands of PKN1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Thr203 of claudin-1, a putative phosphorylation site for MAP kinase, is required to promote the barrier function of tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudins in occluding junctions of humans and flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Crosstalk of tight junction components with signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Transforming growth factor-beta regulation of epithelial tight junction proteins enhances barrier function and blocks enterohemorrhagic Escherichia coli O157:H7-induced increased permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

MAP kinases and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudins regulate the intestinal barrier in response to immune mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Transforming growth factor beta3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Targeting JNK for therapeutic benefit: from junk to gold?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Transcription factor activities and gene expression during mouse mammary gland involution

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Experimental modulation of occluding junctions in a cultured transporting epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

cAMP-dependent chloride secretion mediates tubule enlargement and cyst formation by cultured mammalian collecting duct cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Tumour necrosis factor alpha confers an invasive, transformed phenotype on mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

p38 MAP kinases: beyond the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Tight junction regulation in the mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Hormonal regulation of tight junction closure in the mouse mammary epithelium during the transition from pregnancy to lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Aspirin induces gastric epithelial barrier dysfunction by activating p38 MAPK via claudin-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Biphasic regulation of mammary epithelial resistance by serotonin through activation of multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

The ERK cascade: a prototype of MAPK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Effect of claudins 6 and 9 on paracellular permeability in MDCK II cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

The tight junction: a multifunctional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Epidermal Growth Factor Receptor Activation Differentially Regulates Claudin Expression and Enhances Transepithelial Resistance in Madin-Darby Canine Kidney Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Multifunctional strands in tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Tight junction-based epithelial microenvironment and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Barriers built on claudins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudins and epithelial paracellular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Selective decrease in paracellular conductance of tight junctions: role of the first extracellular domain of claudin-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Antagonistic regulation of tight junction dynamics by glucocorticoids and transforming growth factor-beta in mouse mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

The control of cell motility and epithelial morphogenesis by Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

Glucocorticoid-induced formation of tight junctions in mouse mammary epithelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00084.2009

10.1152/AJPCELL.00084.2009

21 January 2018

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DOI

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15 September 2017

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