Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells. (Q39832869)

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English	Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells.	scientific article

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1 February 2020

Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells (English)

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1 February 2020

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Jacobus J Bosch

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1 February 2020

Bruce R Ksander

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Bruce R Ksander

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1 February 2020

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Michal Lotem

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1 February 2020

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Uzoma K Iheagwara

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1 February 2020

Sarah Reid

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1 February 2020

Minu K Srivastava

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1 February 2020

Julie Wolf

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1 February 2020

Suzanne Ostrand-Rosenberg

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1 February 2020

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26 June 2009

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1 February 2020

Cancer Immunology, Immunotherapy

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1 February 2020

59

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1 February 2020

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1 February 2020

103-112

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1 February 2020

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11 June 2022

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MHC class II transport at a glance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Regulation of secretory vesicle traffic by Rab small GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Major histocompatibility complex class II-peptide complexes internalize using a clathrin- and dynamin-independent endocytosis pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+ T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

MHC class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4(+) T lymphocytes that cross-react with primary and metastatic uveal melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

MHC class II molecules in tumour immunology: prognostic marker and target for immune modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Upregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Dissection of the HLA-DR4 peptide repertoire in endocrine epithelial cells: strong influence of invariant chain and HLA-DM expression on the nature of ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Multiple roles of the invariant chain in MHC class II function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Preferential Th1 immune response in invariant chain-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Biogenesis of the sorting endosome: the role of Rab5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Mice lacking the MHC class II-associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

How MHC class II molecules reach the endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

22 September 2017

The endogenous pathway of MHC class II antigen presentation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

25 September 2017

Prognostic parameters in uveal melanoma: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

25 September 2017

The invariant chain inhibits presentation of endogenous antigens by a human fibroblast cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

25 September 2017

Lung cancer patients' CD4(+) T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

15 June 2018

Major histocompatibility complex class II-dependent unfolding, transport, and degradation of endogenous proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

15 June 2018

Lymphocytes cytotoxic to uveal and skin melanoma cells from peripheral blood of ocular melanoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

15 June 2018

Activation of tumor-specific CD4(+) T lymphocytes by major histocompatibility complex class II tumor cell vaccines: a novel cell-based immunotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

20 August 2018

Very long-term prognosis of patients with malignant uveal melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

20 August 2018

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

20 August 2018

T-cell engagement of dendritic cells rapidly rearranges MHC class II transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

20 August 2018

Non-fastidious, melanoma-specific CD8+ cytotoxic T lymphocytes from choroidal melanoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800822

20 August 2018

Tumor cells present MHC class II-restricted nuclear and mitochondrial antigens and are the predominant antigen presenting cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Class II-associated invariant chain peptide expression on myeloid leukemic blasts predicts poor clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Invariant chain prevents the HLA-DR-restricted presentation of a cytosolic peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allelic differences affecting invariant chain dependency of MHC class II subunit assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melanomas that develop within the eye inhibit lymphocyte proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC class II-transfected tumor cells directly present antigen to tumor-specific CD4+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BALB/c invariant chain mutant mice display relatively efficient maturation of CD4+ T cells in the periphery and secondary proliferative responses elicited upon peptide challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor cells transduced with the MHC class II Transactivator and CD80 activate tumor-specific CD4+ T cells whether or not they are silenced for invariant chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19557412

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00262-009-0729-0

1 reference

Europe PubMed Central

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1 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19557412%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19557412%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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