Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease (Q39844016)

15 September 2017

Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease (English)

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15 September 2017

Ying Wang

1

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15 September 2017

Gunda Millonig

2

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15 September 2017

Jagadeesan Nair

3

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15 September 2017

Eleonora Patsenker

4

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15 September 2017

Felix Stickel

5

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15 September 2017

Sebastian Mueller

6

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15 September 2017

Helmut Bartsch

7

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15 September 2017

Helmut K Seitz

8

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15 September 2017

language of work or name

English

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publication date

1 August 2009

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15 September 2017

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15 September 2017

50

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15 September 2017

2

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15 September 2017

453-461

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The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002.

15 September 2017

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Alcohol and hepatocellular carcinoma

21 January 2018

1 reference

Molecular mechanisms of alcohol-mediated carcinogenesis

21 January 2018

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Cocarcinogenic effects of alcohol in hepatocarcinogenesis

21 January 2018

1 reference

Carcinogenicity of alcoholic beverages

21 January 2018

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Alcohol, oxidative stress and free radical damage

21 January 2018

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Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts.

21 January 2018

1 reference

Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair

21 January 2018

1 reference

Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase

21 January 2018

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Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole

21 January 2018

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Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver

21 January 2018

1 reference

Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepato-carcinogenesis

21 January 2018

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1,N6-etheno-2'-deoxyadenosine and 3,N4-etheno-2'-deoxycytidine detected by monoclonal antibodies in lung and liver DNA of rats exposed to vinyl chloride.

21 January 2018

1 reference

The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver

21 January 2018

1 reference

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

21 January 2018

1 reference

Ethanol enhances the formation of endogenously and exogenously derived adducts in rat hepatic DNA.

21 January 2018

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Formation, detection, and role in carcinogenesis of ethenobases in DNA.

21 January 2018

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Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage

21 January 2018

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CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

21 January 2018

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Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

21 January 2018

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Non-alcoholic steatohepatitis: from cell biology to clinical practice

21 January 2018

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Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice

21 January 2018

1 reference

Interaction of lipid peroxidation products with DNA. A review

21 January 2018

1 reference

21 January 2018

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Structural characterization of adducts formed in the reaction of 2,3-epoxy-4-hydroxynonanal with deoxyguanosine

21 January 2018

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Formation of cyclic deoxyguanosine adducts in Chinese hamster ovary cells by acrolein and crotonaldehyde

21 January 2018

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Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver

21 January 2018

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Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.

21 January 2018

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1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells

21 January 2018

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Quantitative multiplex sequence analysis of mutational hot spots. Frequency and specificity of mutations induced by a site-specific ethenocytosine in M13 viral DNA.

21 January 2018

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Mutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells

21 January 2018

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The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli

21 January 2018

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The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

21 January 2018

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Formation of 1,N6-ethenoadenine and 3,N4-ethenocytosine by lipid peroxidation products and nucleic acid bases

21 January 2018

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7 January 2021

Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol

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7 January 2021

Quantitative Relationship between Amount of Dietary Fat and Severity of Alcoholic Fatty Liver

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7 January 2021

Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells

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7 January 2021

Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans

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7 January 2021

Immunohistochemical detection of 1,N(6)-ethenodeoxyadenosine, a promutagenic DNA adduct, in liver of rats exposed to vinyl chloride or an iron overload

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7 January 2021

1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabeling

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7 January 2021

Regulation of peroxisome proliferator activated receptor alpha-mediated pathways in alcohol fed cytochrome P450 2E1 deficient mice

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7 January 2021

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

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7 January 2021

Identifiers

DOI

10.1002/HEP.22978

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15 September 2017

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