KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer (Q39860040)

15 September 2017

KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer (English)

1 reference

15 September 2017

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1 reference

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7

Robert S Sandler

1 reference

15 September 2017

Jen Jen Yeh

1

1 reference

15 September 2017

Elizabeth D Routh

2

1 reference

15 September 2017

Tara Rubinas

3

1 reference

15 September 2017

Janie Peacock

4

1 reference

15 September 2017

Timothy D Martin

5

1 reference

15 September 2017

Xiang Jun Shen

6

1 reference

15 September 2017

Hong Jin Kim

8

1 reference

15 September 2017

Temitope O Keku

9

1 reference

15 September 2017

Channing J Der

10

1 reference

15 September 2017

1 April 2009

1 reference

Molecular Cancer Therapeutics

15 September 2017

1 reference

15 September 2017

8

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15 September 2017

4

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15 September 2017

834-843

1 reference

describes a project that uses

15 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2729756/fullTextXML

inferred from PubMed Central ID database lookup

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis?

22 September 2017

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Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer

22 September 2017

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22 September 2017

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Distinct requirements for Ras oncogenesis in human versus mouse cells

22 September 2017

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Tissue microarray profiling of cancer specimens and cell lines: opportunities and limitations

22 September 2017

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Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2.

22 September 2017

1 reference

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Understanding Ras: 'it ain't over 'til it's over'.

22 September 2017

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22 September 2017

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Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

22 September 2017

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

22 September 2017

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

22 September 2017

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22 September 2017

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Lessons from hereditary colorectal cancer

22 September 2017

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Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression.

22 September 2017

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Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors

25 September 2017

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Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations

15 June 2018

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Expression and activity of mitogen activated protein kinases in human colorectal carcinoma

15 June 2018

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15 June 2018

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Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

15 June 2018

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Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies

15 June 2018

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20 August 2018

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RAF/RAS oncogenes and mismatch-repair status

20 August 2018

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Downregulation of mitogen-activated protein kinases in human colon cancers

2 December 2018

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https://pubmed.ncbi.nlm.nih.gov/19372556

12 December 2020

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In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19372556

12 December 2020

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Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19372556

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1535-7163.MCT-08-0972

1 reference

15 September 2017

1 reference

15 September 2017

1 reference