Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication. (Q39873967)

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scientific article published on April 1996

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English	Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication.	scientific article published on April 1996

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scholarly article

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16 October 2019

Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication (English)

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16 October 2019

author name string

A M Caliendo

1

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A Savara

2

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16 October 2019

D An

3

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K DeVore

4

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J C Kaplan

5

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16 October 2019

R T D'Aquila

6

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language of work or name

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publication date

1 April 1996

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16 October 2019

number of pages

8

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inferred from page(s)

Journal of Virology

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70

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16 October 2019

4

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16 October 2019

2146-2153

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16 October 2019

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1 reference

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pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

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Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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Rapid and sensitive viral culture method for human immunodeficiency virus type 1.

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

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1 reference

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12 December 2020

based on heuristic

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Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy. AIDS Clinical Trials Group Protocol 116B/117 Team and the Virology Committee Resistance Working Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/8642636

12 December 2020

based on heuristic

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HIV-1 RNA serum-load and resistant viral genotypes during early zidovudine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8642636

12 December 2020

based on heuristic

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Identifiers

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16 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8642636%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

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