CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. (Q39895118)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12569127%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

title

CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals (English)

1 reference

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17 December 2019

0 references

2

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17 December 2019

author name string

Shengkan Jin

1

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17 December 2019

Michael Overholtzer

3

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17 December 2019

Archontoula Stoffel

4

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17 December 2019

Brian T Chait

5

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17 December 2019

Arnold J Levine

6

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17 December 2019

publication date

1 February 2003

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17 December 2019

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17 December 2019

volume

17

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17 December 2019

issue

3

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17 December 2019

page(s)

359-367

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The p53MH algorithm and its application in detecting p53-responsive genes

17 December 2019

cites work

1 reference

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Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

22 September 2017

1 reference

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Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

22 September 2017

1 reference

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Apoptosis and chemoresistance in transgenic cancer models

22 September 2017

1 reference

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Lymphocyte-mediated cytotoxicity.

22 September 2017

1 reference

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Automatic identification of proteins with a MALDI-quadrupole ion trap mass spectrometer.

22 September 2017

1 reference

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

22 September 2017

1 reference

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

22 September 2017

1 reference

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The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

22 September 2017

1 reference

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Structural basis of IAP recognition by Smac/DIABLO

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements

22 September 2017

1 reference

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22 September 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

The API2/MALT1 fusion product may lead to germinal center B cell lymphomas by suppression of apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Tissue-specific splicing of Omi stress-regulated endoprotease leads to an inactive protease with a modified PDZ motif

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Identification and characterization of a p53 homologue in Drosophila melanogaster

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

IAP family proteins--suppressors of apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

p53, the cellular gatekeeper for growth and division

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

p53 is required for radiation-induced apoptosis in mouse thymocytes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

22 September 2017

1 reference

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Structural aspects of the p53 protein in relation to gene evolution

22 September 2017

1 reference

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Drosophila p53 binds a damage response element at the reaper locus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

17 June 2018

1 reference

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Characterization of gene expression of a p53 homologue in the soft-shell clam (Mya arenaria).

17 June 2018

1 reference

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Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

17 June 2018

1 reference

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Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.

20 August 2018

1 reference

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Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

20 August 2018

1 reference

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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

Activation of the reaper gene during ectopic cell killing in Drosophila

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195984

20 August 2018

Apoptosis in development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12569127

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The p53 functional circuit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12569127

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Proteome analysis of polyacrylamide gel-separated proteins visualized by reversible negative staining using imidazole-zinc salts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12569127

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1047003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12569127%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12569127%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

PubMed publication ID

12569127

1 reference