Myc down-regulation affects cyclin D1/cdk4 activity and induces apoptosis via Smac/Diablo pathway in an astrocytoma cell line (Q39895392)

19143767

15 September 2017

title

Myc down-regulation affects cyclin D1/cdk4 activity and induces apoptosis via Smac/Diablo pathway in an astrocytoma cell line (English)

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15 September 2017

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Cecilia Verga Falzacappa

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

author name string

D Amendola

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

M De Salvo

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

R Marchese

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

A Stigliano

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

E Carico

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

E Brunetti

7

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14 May 2020

M Moscarini

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

B Bucci

9

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14 May 2020

publication date

1 February 2009

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15 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

volume

42

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14 May 2020

issue

1

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14 May 2020

page(s)

94-109

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

Identification of multiple cell cycle regulatory functions of p57Kip2 in human T lymphocytes

14 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

Differential expression of myc, max and RB1 genes in human gliomas and glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

21 January 2018

Myc and the cell cycle

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

Repression of cyclin D1: a novel function of MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2008.00576.X

c-MYC: more than just a matter of life and death

21 January 2018

1 reference

12 December 2020

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

1 reference

12 December 2020

Effects of poly(ADP-ribose) polymerase inhibition on cell death and chromosome damage induced by VP16 and bleomycin.

1 reference

12 December 2020

Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.

1 reference

12 December 2020

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

1 reference

12 December 2020

Abrogation of p53-induced cell cycle arrest by c-Myc: evidence for an inhibitor of p21WAF1/CIP1/SDI1.

1 reference

12 December 2020

P-glycoprotein expression in brain tumors

1 reference

12 December 2020

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1 reference

12 December 2020

c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

1 reference

12 December 2020

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

1 reference

12 December 2020

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

12 December 2020

Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases

1 reference

12 December 2020

Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16INK4A as upstream regulators of Myc.

1 reference

12 December 2020

c-MYC apoptotic function is mediated by NRF-1 target genes

1 reference

12 December 2020

The expanding role of mitochondria in apoptosis

1 reference

12 December 2020

Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene

1 reference

12 December 2020

Death and anti-death: tumour resistance to apoptosis

1 reference

12 December 2020

Gaseous nitrogen oxides stimulate cell cycle progression by retinoblastoma phosphorylation via activation of cyclins/Cdks [correction].

1 reference

12 December 2020

Repression of c-Myc responsive genes in cycling cells causes G1 arrest through reduction of cyclin E/CDK2 kinase activity.

1 reference

12 December 2020

Antineoplastic Drug Resistance in Brain Tumors

1 reference

12 December 2020

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

12 December 2020

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

1 reference

12 December 2020

Myc down-regulation induces apoptosis in M14 melanoma cells by increasing p27(kip1) levels

1 reference

12 December 2020

Cyclin A but not cyclin D1 is essential for c-myc-modulated cell-cycle progression

1 reference

12 December 2020

Mechanisms of apoptosis by c-Myc

1 reference

12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

12 December 2020

Dimerization of the amino terminal domain of p57Kip2 inhibits cyclin D1-cdk4 kinase activity

1 reference

12 December 2020

Activation of cyclin D1-kinase in murine fibroblasts lacking both p21(Cip1) and p27(Kip1).

1 reference

12 December 2020

Proteasome inhibitors potentiate etoposide-induced cell death in human astrocytoma cells bearing a mutated p53 isoform

1 reference

12 December 2020

Identification of c-myc responsive genes using rat cDNA microarray.

1 reference

12 December 2020

p21-containing cyclin kinases exist in both active and inactive states

1 reference

12 December 2020

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

1 reference

12 December 2020

Elliptically polarized magnetic fields do not alter immediate early response genes expression levels in human glioblastoma cells.

1 reference

12 December 2020

Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc

1 reference

12 December 2020

Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

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12 December 2020

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12 December 2020

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1 reference

12 December 2020

Negative regulation of the mammalian UV response by Myc through association with Miz-1

1 reference

12 December 2020

New functional activities for the p21 family of CDK inhibitors

1 reference

12 December 2020

The many faces of c-MYC.

1 reference

12 December 2020

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

1 reference

12 December 2020

Activation of c-Myc uncouples DNA replication from activation of G1-cyclin-dependent kinases

1 reference

12 December 2020

Hypoxia stimulates p16 expression and association with cdk4.

1 reference

12 December 2020

Caspase 8: the killer you can't live without.

1 reference

12 December 2020

Resistance of human astrocytoma cells to apoptosis induced by mitochondria-damaging agents: possible implications for anticancer therapy

1 reference

12 December 2020

Glioma: what is the role of c-Myc, hsp90 and telomerase?

1 reference

12 December 2020

Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression

1 reference

12 December 2020

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

12 December 2020

Drug resistance in brain tumors

1 reference

12 December 2020

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

1 reference

12 December 2020

p21 is a universal inhibitor of cyclin kinases

1 reference

12 December 2020

10.1111/J.1365-2184.2008.00576.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496913&resulttype=core&format=json

14 May 2020

19143767

1 reference