Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells (Q39896591)

15 September 2017

title

Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells (English)

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15 September 2017

2

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15 September 2017

M Kochetkova

1

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15 September 2017

S R McColl

series ordinal

3

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15 September 2017

publication date

9 January 2009

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Cell Death & Differentiation

15 September 2017

published in

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15 September 2017

volume

16

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15 September 2017

issue

5

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15 September 2017

page(s)

664-673

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https://scigraph.springernature.com/pub.10.1038/cdd.2008.190

15 September 2017

exact match

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cites work

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JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways.

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

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Dissemination and growth of cancer cells in metastatic sites

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BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation

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Organ selectivity in metastasis: regulation by chemokines and their receptors

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Microtubule-destabilizing agents induce focal adhesion structure disorganization and anoikis in cancer cells

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Activation pathways of alpha4beta1 integrin leading to distinct T-cell cytoskeleton reorganization, Rac1 regulation and Pyk2 phosphorylation.

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CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner

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Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes

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Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation

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Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

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Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

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Cell death: critical control points

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Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development

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Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy

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Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells

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Involvement of chemokine receptors in organ-specific metastasis

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Chemokines and cancer

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https://api.crossref.org/works/10.1038%2FCDD.2008.190

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Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells

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https://api.crossref.org/works/10.1038%2FCDD.2008.190

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Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21

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CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions

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Identifiers

DOI

10.1038/CDD.2008.190

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15 September 2017

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