An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation (Q39897560)

15 September 2017

An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation (English)

1 reference

15 September 2017

0 references

Yun-Young Lee

1

1 reference

15 September 2017

Randal C Cevallos

series ordinal

2

1 reference

15 September 2017

Eric Jan

series ordinal

3

1 reference

15 September 2017

language of work or name

English

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publication date

8 January 2009

1 reference

Journal of Biological Chemistry

15 September 2017

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15 September 2017

284

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11

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15 September 2017

6661-6673

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describes a project that uses

15 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2652341/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

22 September 2017

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

22 September 2017

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Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

22 September 2017

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22 September 2017

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Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency

22 September 2017

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Physical evidence for distinct mechanisms of translational control by upstream open reading frames

22 September 2017

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Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

22 September 2017

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

22 September 2017

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

22 September 2017

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Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

22 September 2017

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

22 September 2017

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22 September 2017

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22 September 2017

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Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

22 September 2017

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

22 September 2017

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Mammalian GADD34, an apoptosis- and DNA damage-inducible gene

22 September 2017

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Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron

22 September 2017

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Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

22 September 2017

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

22 September 2017

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22 September 2017

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Multiple upstream AUG codons mediate translational control of GCN4.

22 September 2017

1 reference

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The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2

22 September 2017

1 reference

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Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI

22 September 2017

1 reference

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Structural features in eukaryotic mRNAs that modulate the initiation of translation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

22 September 2017

1 reference

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Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

uAUG and uORFs in human and rodent 5'untranslated mRNAs

15 June 2018

1 reference

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Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus

15 June 2018

1 reference

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Evolutionarily conserved features of the arginine attenuator peptide provide the necessary requirements for its function in translational regulation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

Translational control by an upstream open reading frame in the HER-2/neu transcript

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

Downstream control of upstream open reading frames

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652341

Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19131336

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M806735200

1 reference

15 September 2017

1 reference

15 September 2017

1 reference