Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling (Q39899713)

15 September 2017

Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling (English)

1 reference

15 September 2017

Hichem Miraoui

1

1 reference

15 September 2017

Karim Oudina

2

1 reference

15 September 2017

Hervé Petite

3

1 reference

15 September 2017

Yukiho Tanimoto

4

1 reference

15 September 2017

Keiji Moriyama

5

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15 September 2017

Pierre J Marie

6

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15 September 2017

language of work or name

English

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publication date

30 December 2008

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Journal of Biological Chemistry

15 September 2017

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15 September 2017

284

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15 September 2017

8

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15 September 2017

4897-4904

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Multilineage potential of adult human mesenchymal stem cells

15 September 2017

1 reference

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Bone marrow stromal stem cells: nature, biology, and potential applications

21 January 2018

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Playing with bone and fat.

21 January 2018

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Osteogenic differentiation of human marrow-derived mesenchymal stem cells

21 January 2018

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Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current views

21 January 2018

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Role of Cbfa1 in osteoblast differentiation and function

21 January 2018

1 reference

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Regulation of osteoblast formation and function

21 January 2018

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Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

21 January 2018

1 reference

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Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation

21 January 2018

1 reference

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Expression profiling and functional analysis of wnt signaling mechanisms in mesenchymal stem cells

21 January 2018

1 reference

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Bone morphogenetic protein regulation of early osteoblast genes in human marrow stromal cells is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase signaling

21 January 2018

1 reference

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Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase

21 January 2018

1 reference

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Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling

21 January 2018

1 reference

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Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation

21 January 2018

1 reference

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Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development

21 January 2018

1 reference

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Fibroblast growth factors, their receptors and signaling

21 January 2018

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Mechanisms underlying differential responses to FGF signaling

21 January 2018

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FGF signaling in the developing endochondral skeleton

21 January 2018

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Fibroblast growth factor signaling controlling osteoblast differentiation

21 January 2018

1 reference

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Basic fibroblast growth factor enhances the growth and expression of the osteogenic phenotype of dexamethasone-treated human bone marrow-derived bone-like cells in culture

21 January 2018

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Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

21 January 2018

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Cellular signaling by fibroblast growth factor receptors

21 January 2018

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Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

21 January 2018

1 reference

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Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

21 January 2018

1 reference

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Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.

21 January 2018

1 reference

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The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2

21 January 2018

1 reference

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FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

21 January 2018

1 reference

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FGFs, their receptors, and human limb malformations: clinical and molecular correlations

21 January 2018

1 reference

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Sulfated glycosaminoglycans mediate the effects of FGF2 on the osteogenic potential of rat calvarial osteoprogenitor cells

21 January 2018

1 reference

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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

21 January 2018

1 reference

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Decreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disorders

21 January 2018

1 reference

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Role of N-cadherin and protein kinase C in osteoblast gene activation induced by the S252W fibroblast growth factor receptor 2 mutation in Apert craniosynostosis

21 January 2018

1 reference

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Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805432200

A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome

21 January 2018

1 reference

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P253R fibroblast growth factor receptor-2 mutation induces RUNX2 transcript variants and calvarial osteoblast differentiation

21 January 2018

1 reference

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

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Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

21 January 2018

1 reference

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Reciprocal control of osteoblast/chondroblast and osteoblast/adipocyte differentiation of multipotential clonal human marrow stromal F/STRO-1(+) cells

21 January 2018

1 reference

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Measurement of the specific lipid content of attached cells in microtiter cultures.

21 January 2018

1 reference

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SOST/sclerostin, an osteocyte-derived negative regulator of bone formation

21 January 2018

1 reference

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Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand

21 January 2018

1 reference

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Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome

21 January 2018

1 reference

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Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts

21 January 2018

1 reference

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Fibroblast growth factor-2 induces osteoblast survival through a phosphatidylinositol 3-kinase-dependent, -beta-catenin-independent signaling pathway

21 January 2018

1 reference

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Increased osteoblast apoptosis in apert craniosynostosis: role of protein kinase C and interleukin-1.

21 January 2018

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Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation

21 January 2018

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A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis.

21 January 2018

1 reference

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A Ser250Trp substitution in mouse fibroblast growth factor receptor 2 (Fgfr2) results in craniosynostosis

21 January 2018

1 reference

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Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse.

21 January 2018

1 reference

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A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis

21 January 2018

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A biodegradable fibrin scaffold for mesenchymal stem cell transplantation

21 January 2018

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Osteogenic differentiation of murine embryonic stem cells is mediated by fibroblast growth factor receptors.

21 January 2018

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Runx2 phosphorylation induced by fibroblast growth factor-2/protein kinase C pathways

21 January 2018

1 reference

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Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- and PKA-dependent pathway

21 January 2018

1 reference

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A novel protein kinase C alpha-dependent signal to ERK1/2 activated by alphaVbeta3 integrin in osteoclasts and in Chinese hamster ovary (CHO) cells

21 January 2018

1 reference

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Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805432200

Functional interaction of protein kinase Calpha with the tyrosine kinases Syk and Src in human platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805432200

Fibroblast growth factor-2 (FGF-2) increases N-cadherin expression through protein kinase C and Src-kinase pathways in human calvaria osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805432200

Basic fibroblast growth factor stimulates fibronectin expression through phospholipase C gamma, protein kinase C alpha, c-Src, NF-kappaB, and p300 pathway in osteoblasts

21 January 2018

1 reference

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Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells

21 January 2018

1 reference

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RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis

21 January 2018

1 reference

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Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M805432200

1 reference

15 September 2017

1 reference