Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis. (Q39899938)

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English	Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.	scientific article

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18 January 2020

Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis (English)

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18 January 2020

Jan-Wilhelm Kornfeld

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18 January 2020

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18 January 2020

Richard Moriggl

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18 January 2020

Josef Penninger

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18 January 2020

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18 January 2020

Monica Musteanu

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18 January 2020

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18 January 2020

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18 January 2020

Wolfgang Mikulits

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18 January 2020

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18 January 2020

Emilio Casanova

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18 January 2020

Michael Trauner

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Michael Trauner

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18 January 2020

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Judith Gumhold

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18 January 2020

Doris Schneller

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Doris Schneller

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18 January 2020

Harald Esterbauer

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Harald Esterbauer

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18 January 2020

Daniel Schramek

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Daniel Schramek

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18 January 2020

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Franziska van Zijl

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18 January 2020

Markus Mair

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18 January 2020

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1 April 2010

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

1319-1326

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18 January 2020

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.

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22 September 2017

Prolactin's role in the early stages of liver regeneration in rats.

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22 September 2017

Transcriptional activation by growth hormone of HNF-6-regulated hepatic genes, a potential mechanism for improved liver repair during biliary injury in mice

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22 September 2017

The EGF receptor is required for efficient liver regeneration

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22 September 2017

Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options

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22 September 2017

Bile salts regulate proliferation and apoptosis of liver cells by modulating the IGF1 system

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22 September 2017

Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression

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22 September 2017

Liver fibrosis: cellular mechanisms of progression and resolution

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22 September 2017

Growth hormone regulation of sex-dependent liver gene expression

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Hormonal regulation of hepatic organic anion transporting polypeptides

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22 September 2017

In vivo analysis of growth hormone receptor signaling domains and their associated transcripts

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22 September 2017

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22 September 2017

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22 September 2017

Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5.

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22 September 2017

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

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22 September 2017

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22 September 2017

High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum

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22 September 2017

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

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25 September 2017

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25 September 2017

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17 June 2018

Cirrhotic liver expresses low levels of the full-length and truncated growth hormone receptors

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17 June 2018

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17 June 2018

Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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20 August 2018

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Short-term effect of recombinant human growth hormone in patients with alcoholic cirrhosis

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21 January 2018

Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20162728

12 December 2020

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Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20162728

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A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues

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https://pubmed.ncbi.nlm.nih.gov/20162728

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Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model

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1 reference

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Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20162728

12 December 2020

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inferred from PubMed ID database lookup

Growth hormone-stimulated IGF-1 generation in cirrhosis reflects hepatocellular dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20162728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of STAT5 (signal transducer and activator of transcription 5) and HNF-4 (hepatocyte nuclear factor 4) in the transcriptional control of the hnf6 gene by growth hormone

1 reference

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12 December 2020

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1 reference

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7 January 2021

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inferred from DOI database lookup

Identifiers

10.1002/HEP.23469

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20162728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20162728%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

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18 January 2020

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