S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation (Q39900962)

15 September 2017

S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation (English)

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15 September 2017

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Rachel L Yamnik

1

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15 September 2017

Alla Digilova

2

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15 September 2017

Daphne C Davis

3

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15 September 2017

Z Nilly Brodt

4

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15 September 2017

Christopher J Murphy

5

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15 September 2017

Marina K Holz

6

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15 September 2017

language of work or name

English

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publication date

27 December 2008

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Journal of Biological Chemistry

15 September 2017

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15 September 2017

284

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15 September 2017

6361-6369

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15 September 2017

10

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Sirolimus: its discovery, biological properties, and mechanism of action

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Identification and characterization of a mitogen-activated S6 kinase

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p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

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Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

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SKAR is a specific target of S6 kinase 1 in cell growth control

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Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

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S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

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mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

21 January 2018

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SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs

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A new mutational AKTivation in the PI3K pathway

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Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis

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Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer

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The 17q23 amplicon and breast cancer

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Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients

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Determinants of rapamycin sensitivity in breast cancer cells

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pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

21 January 2018

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Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

21 January 2018

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S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.

21 January 2018

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The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

21 January 2018

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RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation

21 January 2018

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Structural and functional analysis of pp70S6k

21 January 2018

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Identification of a conserved motif required for mTOR signaling

21 January 2018

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Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation

21 January 2018

1 reference

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Rapid chemosensitivity assay with human normal and tumor cells in vitro

21 January 2018

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Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.

21 January 2018

1 reference

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mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

21 January 2018

1 reference

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Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer

21 January 2018

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Involvement of steroid hormone and growth factor cross-talk in endocrine response in breast cancer

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mTOR: the mammalian target of replication

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Lymphangioleiomyomatosis: A review

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Lymphangioleiomyomatosis and tuberous sclerosis complex

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Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

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1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M807532200

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15 September 2017

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