Aldose reductase inhibitor fidarestat attenuates leukocyte-endothelial interactions in experimental diabetic rat retina in vivo (Q39918429)

15 September 2017

Aldose reductase inhibitor fidarestat attenuates leukocyte-endothelial interactions in experimental diabetic rat retina in vivo (English)

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15 September 2017

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Tomoaki Hattori

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15 September 2017

Akihisa Matsubara

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2

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15 September 2017

Kaori Taniguchi

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15 September 2017

Yuichiro Ogura

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4

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15 September 2017

1 February 2010

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15 September 2017

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15 September 2017

35

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2

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146-154

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The sorbitol pathway and the complications of diabetes

15 September 2017

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The polyol pathway as a mechanism for diabetic retinopathy: attractive, elusive, and resilient

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Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications.

21 January 2018

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Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.

21 January 2018

1 reference

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Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications for novel therapies

21 January 2018

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Long-term treatment with fidarestat suppresses the development of diabetic retinopathy in STZ-induced diabetic rats

21 January 2018

1 reference

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Suppressive effects of selectin inhibitor SKK-60060 on the leucocyte infiltration during endotoxin induced uveitis

21 January 2018

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Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition

21 January 2018

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Protective effects of selectin ligands/inhibitor (SKK-60060) against retinal ischemia-reperfusion injury

21 January 2018

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Pitavastatin attenuates leukocyte-endothelial interactions induced by ischemia-reperfusion injury in the rat retina

21 January 2018

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Effect of posterior sub-tenon administration of triamcinolone acetonide on leukocyte dynamics in rat retinal microcirculation after panretinal photocoagulation

21 January 2018

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Lipid hydroperoxide stimulates leukocyte-endothelium interaction in the retinal microcirculation

21 January 2018

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Hypercholesterolemia induces leukocyte entrapment in the retinal microcirculation of rats

21 January 2018

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A new fluorescent imaging procedure in vivo for evaluation of the retinal microcirculation in rats

21 January 2018

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Comparative expression profiles of Trk receptors and Shc-related phosphotyrosine adapters during retinal development: potential roles of N-Shc/ShcC in brain-derived neurotrophic factor signal transduction and modulation

21 January 2018

1 reference

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Enhanced superoxide radical production by stimulated polymorphonuclear leukocytes in a cat model of diabetes

21 January 2018

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High glucose exacerbates neutrophil adhesion to human retinal endothelial cells

21 January 2018

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Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

21 January 2018

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Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins.

21 January 2018

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Identification of fructose 3-phosphate in the lens of diabetic rats

21 January 2018

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Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy

21 January 2018

1 reference

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Electron microscopic immunocytochemical evidence for the mechanism of blood-retinal barrier breakdown in galactosemic rats and its association with aldose reductase expression and inhibition

21 January 2018

1 reference

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Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers

21 January 2018

1 reference

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Protein kinase C activation and the development of diabetic complications

21 January 2018

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Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice

21 January 2018

1 reference

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Inhibition of aldose reductase attenuates TNF-alpha-induced expression of adhesion molecules in endothelial cells

21 January 2018

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Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells

21 January 2018

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Nitric oxide regulates the polyol pathway of glucose metabolism in vascular smooth muscle cells

21 January 2018

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Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages

21 January 2018

1 reference

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Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

21 January 2018

1 reference

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10.3109/02713680903447918

21 January 2018

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15 September 2017

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