Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase. (Q39921876)

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25 December 2019

title

Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase (English)

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25 December 2019

1

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25 December 2019

author name string

Anne Rogers

2

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25 December 2019

Joanna Treloar

3

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25 December 2019

Bo R Jorgensen

4

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25 December 2019

John O Miners

5

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25 December 2019

Robyn Meech

6

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25 December 2019

language of work or name

English

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publication date

3 November 2008

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

283

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25 December 2019

issue

52

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25 December 2019

page(s)

36205-36210

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Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics

25 December 2019

cites work

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The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.

22 September 2017

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Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.

22 September 2017

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22 September 2017

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Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7

22 September 2017

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Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver

22 September 2017

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Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

22 September 2017

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Development of 17alpha-estradiol as a neuroprotective therapeutic agent: rationale and results from a phase I clinical study

22 September 2017

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22 September 2017

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Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease

22 September 2017

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Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches.

22 September 2017

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Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7

22 September 2017

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Human UDP-glucuronosyltransferases: metabolism, expression, and disease

22 September 2017

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Structural and functional studies of UDP-glucuronosyltransferases

22 September 2017

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The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

22 September 2017

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The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26

22 September 2017

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Ursodeoxycholic acid treatment of cholesterol gallstone disease.

22 September 2017

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Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5'-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes

22 September 2017

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Drug glucuronidation in humans

22 September 2017

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Bile acid N-acetylglucosaminidation. In vivo and in vitro evidence for a selective conjugation reaction of 7 beta-hydroxylated bile acids in humans

22 September 2017

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A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini

22 September 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

22 September 2017

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The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

22 September 2017

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Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

25 September 2017

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Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1alpha promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins

25 September 2017

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Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

25 September 2017

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25 September 2017

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The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases

17 June 2018

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The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases

17 June 2018

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Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.

20 August 2018

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Acyl glucuronidation and glucosidation of a new and selective endothelin ET(A) receptor antagonist in human liver microsomes

20 August 2018

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Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes

20 August 2018

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Positions of conjugation of bile acids with glucose and N-acetylglucosamine in vitro.

20 August 2018

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Bile acid N-acetylglucosaminides. Formation by microsomal N-acetylglucosaminyltransferases in human liver and kidney.

20 August 2018

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12 December 2020

The major metabolites of ursodeoxycholic acid in human urine are conjugated with N-acetylglucosamine

1 reference

12 December 2020

Enzyme immunoassay for the measurement of 17alpha-estradiol 17-N-acetylglucosaminide in rabbit urine

1 reference

12 December 2020

Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7

1 reference

12 December 2020

The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site

1 reference

12 December 2020

Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M807961200

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18981171%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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25 December 2019

PubMed publication ID

18981171

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