Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells (Q39935218)

15 September 2017

title

Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells (English)

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15 September 2017

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T R Wilson

1

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15 September 2017

M McEwan

2

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15 September 2017

K McLaughlin

3

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15 September 2017

C Le Clorennec

4

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15 September 2017

W L Allen

5

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15 September 2017

D A Fennell

6

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15 September 2017

P G Johnston

7

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15 September 2017

D B Longley

8

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15 September 2017

language of work or name

English

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publication date

29 September 2008

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15 September 2017

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15 September 2017

volume

28

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15 September 2017

issue

1

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15 September 2017

page(s)

63-72

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https://scigraph.springernature.com/pub.10.1038/onc.2008.366

15 September 2017

exact match

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cites work

The Bcl-2 apoptotic switch in cancer development and therapy

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Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells.

21 January 2018

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Death receptors: signaling and modulation

21 January 2018

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Death receptors leave a caspase footprint that Smacs of XIAP.

21 January 2018

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Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage.

21 January 2018

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

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X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

21 January 2018

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X-linked inhibitor of apoptosis protein as a therapeutic target

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

IAP family proteins--suppressors of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

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21 January 2018

Till death do us part.

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Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.

21 January 2018

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Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

21 January 2018

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Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells

21 January 2018

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Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells

21 January 2018

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Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells

21 January 2018

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Mitochondrial control of cell death

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Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis

21 January 2018

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Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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c-FLIP inhibits chemotherapy-induced colorectal cancer cell death

21 January 2018

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c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis

21 January 2018

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Defining characteristics of Types I and II apoptotic cells in response to TRAIL.

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Two CD95 (APO-1/Fas) signaling pathways

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The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.

21 January 2018

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c-FLIP: a key regulator of colorectal cancer cell death

21 January 2018

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Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

21 January 2018

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Role of BAX in the apoptotic response to anticancer agents

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Bax expression decreases significantly from primary tumor to metastasis in colorectal cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Low expression of Bax predicts poor prognosis in patients with locally advanced esophageal cancer treated with definitive chemoradiotherapy

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Increased expression of cFLIP(L) in colonic adenocarcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

XIAP expression correlates with monocytic differentiation in adult de novo AML: impact on prognosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

c-Flip protein expression in Burkitt's lymphomas is associated with a poor clinical outcome

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

Overexpression of cellular FLICE-inhibitory protein (FLIP) in gastric adenocarcinoma.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.366

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.366

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15 September 2017

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