Differential effects of triptolide and tetrandrine on activation of COX-2, NF-kappaB, and AP-1 and virus production in dengue virus-infected human lung cells. (Q39970649)

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English	Differential effects of triptolide and tetrandrine on activation of COX-2, NF-kappaB, and AP-1 and virus production in dengue virus-infected human lung cells.	scientific article

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9 January 2020

Differential effects of triptolide and tetrandrine on activation of COX-2, NF-kappaB, and AP-1 and virus production in dengue virus-infected human lung cells (English)

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9 January 2020

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Jun-Ting Liou

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Zih-Yan Chen

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Shih-Ping Yang

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Deh-Ming Chang

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Chun-Chin Liang

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Jenn-Haung Lai

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6 May 2008

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European Journal of Pharmacology

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1-3

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9 January 2020

Regulation of human polyomavirus JC virus gene transcription by AP-1 in glial cells.

1 reference

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12 December 2020

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The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression

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Antiviral agents from plants and herbs: a systematic review

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Inhibition of activator protein 1 activity and neoplastic transformation by aspirin

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12 December 2020

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Cyclooxygenase-1 and -2 are required for production of infectious pseudorabies virus

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The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression

1 reference

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12 December 2020

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Inhibition of NF-kappa B by sodium salicylate and aspirin

1 reference

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12 December 2020

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Aspirin attenuates cytomegalovirus infectivity and gene expression mediated by cyclooxygenase-2 in coronary artery smooth muscle cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

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Inhibition of cyclooxygenase activity reduces rotavirus infection at a postbinding step

1 reference

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12 December 2020

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Plant alkaloid tetrandrine and its analog block CD28-costimulated activities of human peripheral blood T cells: potential immunosuppressants in transplantation immunology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

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Human cytomegalovirus induced cyclooxygenase-2 in human retinal pigment epithelial cells augments viral replication through a prostaglandin pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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Triptolide inhibits COX-2 expression via NF-kappa B pathway in astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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Autoimmune pathogenesis in dengue virus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrandrine inhibits proinflammatory cytokines, iNOS and COX-2 expression in human monocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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Cyclooxygenases and prostaglandins: shaping up the immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

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Innate immune responses: crosstalk of signaling and regulation of gene transcription

1 reference

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12 December 2020

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In vitro activity of acetylsalicylic acid on replication of varicella-zoster virus.

1 reference

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12 December 2020

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Novel antiviral agents: a medicinal plant perspective

1 reference

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12 December 2020

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Anti-inflammatory lipid mediators and insights into the resolution of inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

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Salicylates inhibit flavivirus replication independently of blocking nuclear factor kappa B activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

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Reciprocal interactions between human T-lymphotropic virus type 1 and prostaglandins: implications for viral transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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Cross-talks between cyclooxygenase-2 and tumor suppressor protein p53: Balancing life and death during inflammatory stress and carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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The role and regulation of COX-2 during viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspirin differentially regulates endotoxin-induced IL-12 and TNF-alpha production in human dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of Japanese encephalitis virus infection by non-steroidal anti-inflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting effects of cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response to influenza A viral infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EBV suppresses prostaglandin E2 biosynthesis in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new view of prostaglandin E regulation of the immune response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

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Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection of human dendritic cells by dengue virus causes cell maturation and cytokine production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RSV-induced prostaglandin E2 production occurs via cPLA2 activation: role in viral replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prophylactic use of cyclooxygenase inhibitors in recurrent herpes simplex infections.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triptolide attenuates endotoxin- and staphylococcal exotoxin-induced T-cell proliferation and production of cytokines and chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signalling networks regulating cyclooxygenase-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triptolide impairs dendritic cell migration by inhibiting CCR7 and COX-2 expression through PI3-K/Akt and NF-kappaB pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dengue viruses can infect human primary lung epithelia as well as lung carcinoma cells, and can also induce the secretion of IL-6 and RANTES.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB and virus infection: who controls whom

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Tripterygium wilfordii hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular nucleotides induce COX-2 up-regulation and prostaglandin E2 production in human A549 alveolar type II epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between glucocorticoid receptor and AP-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AP-1 function and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Western and Chinese antirheumatic drug-induced T cell apoptotic DNA damage uses different caspase cascades and is independent of Fas/Fas ligand interaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological interactions between herpesviruses and cyclooxygenase enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carvedilol, a new antioxidative β-blocker, blocks in vitro human peripheral blood T cell activation by downregulating NF-κB activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cyclooxygenases in inflammation, cancer, and development

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plant alkaloid tetrandrine downregulates IkappaBalpha kinases-IkappaBalpha-NF-kappaB signaling pathway in human peripheral blood T cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of COX-2 in human airways and cultured airway epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostanoids and their receptors that modulate dendritic cell-mediated immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Tetrandrine on LPS-induced NF-kappaB activation in isolated pancreatic acinar cells of rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of indomethacin, prostaglandin E2 and interferon on the multiplication of herpes simplex virus type 1 in human lymphoid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity to macrophages of tetrandrine, an antisilicosis alkaloid, accompanied by an overproduction of prostaglandins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chinese herbs as immunomodulators and potential disease-modifying antirheumatic drugs in autoimmune disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18565510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EJPHAR.2008.04.056

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18565510%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18565510%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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