Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy (Q40004498)

19 February 2018

title

Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy (English)

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19 February 2018

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7

Patrick Hwu

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19 February 2018

Jagannadha Sastry

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object named as

Jagannadha K Sastry

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19 February 2018

author name string

Prakash Thapa

1

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19 February 2018

Guodong Zhang

2

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19 February 2018

Chengfeng Xia

3

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19 February 2018

Alexander Gelbard

4

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19 February 2018

Willem W Overwijk

5

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19 February 2018

Chengwen Liu

6

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19 February 2018

David Z Chang

8

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19 February 2018

Amy Courtney

9

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19 February 2018

Peng G Wang

11

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19 February 2018

Chun Li

12

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19 February 2018

Dapeng Zhou

13

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19 February 2018

language of work or name

English

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publication date

5 February 2009

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19 February 2018

published in

Vaccine

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19 February 2018

volume

27

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19 February 2018

issue

25-26

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19 February 2018

page(s)

3484-3488

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19 February 2018

alpha-Galactosylceramide enhances the protective and therapeutic effects of tumor cell based vaccines for ovarian tumors

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Invariant NKT cells sustain specific B cell responses and memory

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Glycolipid antigen induces long-term natural killer T cell anergy in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Lysosomal glycosphingolipid recognition by NKT cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Testing the NKT cell hypothesis of human IDDM pathogenesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand, alpha-galactosylceramide

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

OX40 signaling directly triggers the antitumor effects of NKT cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

A single intranasal immunization with inactivated influenza virus and alpha-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Targeting of antigen to dendritic cells with poly(gamma-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

alpha-Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5772602

Mediastinal lymph node CD8alpha- DC initiate antigen presentation following intranasal coadministration of alpha-GalCer

20 August 2018

1 reference

12 December 2020

Delivery by Cationic Gelatin Nanoparticles Strongly Increases the Immunostimulatory Effects of CpG Oligonucleotides

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12 December 2020

A modified alpha-galactosyl ceramide for staining and stimulating natural killer T cells

1 reference

12 December 2020

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

1 reference

12 December 2020

KRN7000, a novel immunomodulator, and its antitumor activities

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12 December 2020

10.1016/J.VACCINE.2009.01.047

Identifiers

DOI

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19 February 2018

PMCID

5772602

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19 February 2018

PubMed ID

19200815

1 reference

19 February 2018