Clusterin activates survival through the phosphatidylinositol 3-kinase/Akt pathway (Q40005641)

16 September 2017

Clusterin activates survival through the phosphatidylinositol 3-kinase/Akt pathway (English)

1 reference

16 September 2017

Hayet Ammar

1

1 reference

PubMed ID

18321852

16 September 2017

Jean L Closset

series ordinal

2

1 reference

PubMed ID

18321852

16 September 2017

language of work or name

English

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publication date

5 March 2008

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Journal of Biological Chemistry

16 September 2017

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16 September 2017

283

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16 September 2017

19

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16 September 2017

12851-12861

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Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis

16 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Lack of association between enhanced TRPM-2/clusterin expression and increased apoptotic activity in sex-hormone-induced prostatic dysplasia of the Noble rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Synthesis and functional analyses of nuclear clusterin, a cell death protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Clusterin decreases oxidative stress in lung fibroblasts exposed to cigarette smoke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Multiple receptors mediate apoJ-dependent clearance of cellular debris into nonprofessional phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Long-term androgen-ablation causes increased resistance to PI3K/Akt pathway inhibition in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Bcl-xL Mediates a Survival Mechanism Independent of the Phosphoinositide 3-Kinase/Akt Pathway in Prostate Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Nuclear translocation of a clusterin isoform is associated with induction of anoikis in SV40-immortalized human prostate epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Cytotoxic sensitivity to tumor necrosis factor-alpha in PC3 and LNCaP prostatic cancer cells is regulated by extracellular levels of SGP-2 (clusterin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Differential effects of clusterin/apolipoprotein J on cellular growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Clusterin inhibits apoptosis by interacting with activated Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Knock-down of the cytoprotective gene, clusterin, to enhance hormone and chemosensitivity in prostate and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Nuclear clusterin accumulation during heat shock response: implications for cell survival and thermo-tolerance induction in immortalized and prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

PKB and megalin determine the survival or death of renal proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

Cellular signalling by lipoprotein receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800403200

21 January 2018

Identifiers

DOI

10.1074/JBC.M800403200

1 reference

16 September 2017

1 reference

PubMed ID

18321852