Synthesis, characterization, and in vitro assay of folic acid conjugates of 3'-azido-3'-deoxythymidine (AZT): toward targeted AZT based anticancer therapeutics. (Q40023090)

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scientific article published on February 2008

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English	Synthesis, characterization, and in vitro assay of folic acid conjugates of 3'-azido-3'-deoxythymidine (AZT): toward targeted AZT based anticancer therapeutics.	scientific article published on February 2008

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scholarly article

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1 January 2020

Synthesis, characterization, and in vitro assay of folic acid conjugates of 3'-azido-3'-deoxythymidine (AZT): toward targeted AZT based anticancer therapeutics (English)

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1 January 2020

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Patrick J Sinko

5

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1 January 2020

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Anthony R Vortherms

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1 January 2020

Robert P Doyle

2

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1 January 2020

Dayuan Gao

3

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1 January 2020

Olivia Debrah

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1 January 2020

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1 February 2008

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1 January 2020

Nucleosides, Nucleotides & Nucleic Acids

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1 January 2020

27

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1 January 2020

2

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1 January 2020

173-185

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1 January 2020

3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity

1 reference

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Overexpression of folate binding protein in ovarian cancers.

1 reference

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The effect of splenopentin (DA SP-5) on in vitro myelopoiesis and on AZT-induced bone marrow toxicity

1 reference

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Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

1 reference

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Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds

1 reference

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

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22 September 2017

Red blood cell alloimmunization in transfused patients on AZT

1 reference

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22 September 2017

Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis

1 reference

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22 September 2017

Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues

1 reference

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22 September 2017

Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine.

1 reference

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25 September 2017

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25 September 2017

Synthesis, purification, and tumor cell uptake of 67Ga-deferoxamine--folate, a potential radiopharmaceutical for tumor imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729114

25 September 2017

Cellular targets of 3'-azido-3'-deoxythymidine: an early (non-delayed) effect on oxidative phosphorylation

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Receptor-targeted gene delivery via folate-conjugated polyethylenimine

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729114

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Mitochondrial sensitivity to AZT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2729114

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Cyclic induction of senescence with intermittent AZT treatment accelerates both apoptosis and telomere loss.

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20 August 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18205071

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Microenvironmental toxicity of azidothymidine: partial sparing with hemin

1 reference

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10.1080/15257770701795946

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Europe PubMed Central

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1 January 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18205071%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

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Europe PubMed Central

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1 January 2020

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