Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin (Q40034391)

16 September 2017

Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin (English)

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16 September 2017

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Alistair Boath

1

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16 September 2017

Christine Graf

2

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16 September 2017

Emilie Lidome

3

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16 September 2017

Thomas Ullrich

4

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16 September 2017

Peter Nussbaumer

5

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16 September 2017

Frédéric Bornancin

6

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16 September 2017

language of work or name

English

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publication date

16 December 2007

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Journal of Biological Chemistry

16 September 2017

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16 September 2017

283

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16 September 2017

13

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16 September 2017

8517-8526

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The ins and outs of sphingolipid synthesis

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Biologically active sphingolipids in cancer pathogenesis and treatment

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Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

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Translational aspects of sphingolipid metabolism

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The metabolism and function of sphingolipids and glycosphingolipids.

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Ceramide: physiological and pathophysiological aspects

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The role of sphingosine and ceramide kinases in inflammatory responses

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Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization

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The formation of ceramide-1-phosphate during neutrophil phagocytosis and its role in liposome fusion

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Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release

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Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2

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Ceramide kinase is a mediator of calcium-dependent degranulation in mast cells

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Ceramide 1-phosphate enhances calcium entry through voltage-operated calcium channels by a protein kinase C-dependent mechanism in GH4C1 rat pituitary cells

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Ceramide-1-P induces Ca2+ mobilization in Jurkat T-cells by elevation of Ins(1,4,5)-P3 and activation of a store-operated calcium channel

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Dopamine release in PC12 cells is mediated by Ca(2+)-dependent production of ceramide via sphingomyelin pathway

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Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway

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Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry

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Fluorescence-labeled sphingosines as substrates of sphingosine kinases 1 and 2.

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Molecular cloning and functional characterization of murine sphingosine kinase

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Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy

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Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain

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Calmodulin is involved in the Ca2+-dependent activation of ceramide kinase as a calcium sensor

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Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells

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Molecular machinery for non-vesicular trafficking of ceramide

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A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor

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1 reference

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A novel inhibitor of ceramide trafficking from the endoplasmic reticulum to the site of sphingomyelin synthesis.

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1 reference

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Sphingolipid metabolism in cultured fibroblasts: microscopic and biochemical studies employing a fluorescent ceramide analogue

21 January 2018

1 reference

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Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane

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1 reference

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Dissection of the Golgi complex. I. Monensin inhibits the transport of viral membrane proteins from medial to trans Golgi cisternae in baby hamster kidney cells infected with Semliki Forest virus

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1 reference

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Ceramide 1-phosphate phosphatase activity in brain

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Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis

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Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide

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A critical beta6-beta7 loop in the pleckstrin homology domain of ceramide kinase

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CERT and intracellular trafficking of ceramide

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The mitochondria-associated endoplasmic-reticulum subcompartment (MAM fraction) of rat liver contains highly active sphingolipid-specific glycosyltransferases

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Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions

21 January 2018

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Identification of a family of animal sphingomyelin synthases

21 January 2018

1 reference

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The interaction between the pleckstrin homology domain of ceramide kinase and phosphatidylinositol 4,5-bisphosphate regulates the plasma membrane targeting and ceramide 1-phosphate levels

21 January 2018

1 reference

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Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M707107200

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16 September 2017

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