TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis (Q40035477)

16 September 2017

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis (English)

1 reference

16 September 2017

Niklas Finnberg

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16 September 2017

Andres J P Klein-Szanto

series ordinal

2

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16 September 2017

Wafik S El-Deiry

series ordinal

3

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16 September 2017

language of work or name

English

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publication date

1 January 2008

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Journal of Clinical Investigation

16 September 2017

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16 September 2017

118

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16 September 2017

111-123

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16 September 2017

1

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describes a project that uses

16 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2129232/fullTextXML

inferred from PubMed Central ID database lookup

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Radiation and the microenvironment - tumorigenesis and therapy

22 September 2017

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Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.

22 September 2017

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DR5 knockout mice are compromised in radiation-induced apoptosis

22 September 2017

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Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.

22 September 2017

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Suppression of tumorigenesis by the p53 target PUMA

22 September 2017

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22 September 2017

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

22 September 2017

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Critical roles of TRAIL in hepatic cell death and hepatic inflammation.

22 September 2017

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Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

22 September 2017

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Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

22 September 2017

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

22 September 2017

1 reference

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

22 September 2017

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INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

22 September 2017

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22 September 2017

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

22 September 2017

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Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4

22 September 2017

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Transcriptional regulation of the heat shock protein genes by STAT family transcription factors.

22 September 2017

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Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter

22 September 2017

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Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

22 September 2017

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

22 September 2017

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N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation

22 September 2017

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

22 September 2017

1 reference

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A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

22 September 2017

1 reference

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p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia

22 September 2017

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Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

22 September 2017

1 reference

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Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

25 September 2017

1 reference

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Tissue-specific induction of p53 targets in vivo.

25 September 2017

1 reference

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

17 June 2018

1 reference

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Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

17 June 2018

1 reference

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

17 June 2018

1 reference

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p53 is a suppressor of inflammatory response in mice.

17 June 2018

1 reference

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CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2129232

TRAIL-R as a negative regulator of innate immune cell responses.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2129232

Heterozygous p53-deficient (+/-) mice develop fewer p53-negative preneoplastic focal liver lesions in response to treatment with diethylnitrosamine than do wild-type (+/+) mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2129232

Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2129232

Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2129232

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

20 August 2018

1 reference

12 December 2020

Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an Emu-myc transgene

1 reference

12 December 2020

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice

1 reference

12 December 2020

Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Burkitt's lymphoma cell lines

1 reference

12 December 2020

Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes

1 reference

12 December 2020

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

12 December 2020

Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in E mu L-MYC transgenic mice but not in animals infected with MoMuLV

1 reference

12 December 2020

P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis

1 reference

12 December 2020

Loss of TRAIL-R does not affect thymic or intestinal tumor development in p53 and adenomatous polyposis coli mutant mice

1 reference

12 December 2020

Cutting Edge: TRAIL Deficiency Accelerates Hematological Malignancies

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI29900

1 reference

release_ufkekr5qtzh2zmuhfj7koodtwu

16 September 2017

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Fatcat

https://api.fatcat.wiki/v0/release/ufkekr5qtzh2zmuhfj7koodtwu

24 November 2022

mapped directly with Wikidata item

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16 September 2017

1 reference