A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2. (Q40040751)

16 September 2017

A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2. (English)

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16 September 2017

Katerina Sidera

1

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16 September 2017

Maria Gaitanou

2

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16 September 2017

Dimitris Stellas

3

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16 September 2017

Rebecca Matsas

4

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16 September 2017

Evangelia Patsavoudi

5

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16 September 2017

language of work or name

English

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publication date

5 December 2007

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Journal of Biological Chemistry

16 September 2017

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16 September 2017

283

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16 September 2017

4

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16 September 2017

2031-2041

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Hsp90 & Co. - a holding for folding

16 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

Hsp90: a specialized but essential protein-folding tool

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

Heat-shock protein 90, a chaperone for folding and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Steroid receptor interactions with heat shock protein and immunophilin chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Reduced levels of hsp90 compromise steroid receptor action in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

21 January 2018

Heat shock protein 90.

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

HSP90 and the chaperoning of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

ErbB2 degradation mediated by the co-chaperone protein CHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

Untangling the ErbB signalling network

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

The deaf and the dumb: the biology of ErbB-2 and ErbB-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Signal transduction and oncogenesis by ErbB/HER receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

21 January 2018

1 reference

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Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.

21 January 2018

1 reference

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Identification of a novel neuron-specific surface antigen in the developing nervous system, by monoclonal antibody 4C5.

21 January 2018

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 January 2018

1 reference

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Purification and Characterization of Neuron-Specific Surface Antigen Defined by Monoclonal Antibody BM88

21 January 2018

1 reference

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Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability in vitro

21 January 2018

1 reference

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Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton

21 January 2018

1 reference

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Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Regulation of nuclear retention of glucocorticoid receptor by nuclear Hsp90.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M701803200

Signalling shortcuts: cell-surface receptors in the nucleus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Nuclear localization and possible functions of receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase

21 January 2018

1 reference

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Differential regulation of components of the focal adhesion complex by heregulin: role of phosphatase SHP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Role of the p70(S6K) pathway in regulating the actin cytoskeleton and cell migration

21 January 2018

1 reference

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PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration

21 January 2018

1 reference

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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

21 January 2018

1 reference

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Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

The ErbB/HER receptor protein-tyrosine kinases and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

21 January 2018

1 reference

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Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metalloproteinase-9 expression in human monocytic U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

High HSP90 expression is associated with decreased survival in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701803200

21 January 2018

Identifiers

DOI

10.1074/JBC.M701803200

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16 September 2017

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