Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway (Q40047094)

16 September 2017

Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway (English)

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16 September 2017

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Santiago Rodriguez de Córdoba

16 September 2017

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16 September 2017

David Vilchez

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Susana Ros

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Susana Ros

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author name string

Maria Carmen Solaz-Fuster

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16 September 2017

José Vicente Gimeno-Alcañiz

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16 September 2017

Maria Elena Fernandez-Sanchez

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16 September 2017

Belen Garcia-Fojeda

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16 September 2017

Olga Criado Garcia

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16 September 2017

Jorge Dominguez

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16 September 2017

Mar Garcia-Rocha

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16 September 2017

Maribel Sanchez-Piris

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16 September 2017

Carmen Aguado

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16 September 2017

Erwin Knecht

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16 September 2017

Jose Serratosa

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16 September 2017

Joan Josep Guinovart

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16 September 2017

20 November 2007

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16 September 2017

Human Molecular Genetics

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16 September 2017

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16 September 2017

5

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16 September 2017

667-678

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Progressive familial myoclonic epilepsy in three families: its clinical features and pathological basis.

16 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Beitrag zur Histopathologie der myoklonischen Epilepsie

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Studies in myoclonus epilepsy (Lafora body form). II. Polyglucosans in the systemic deposits of myoclonus epilepsy and in corpora amylacea

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Studies in myoclonus epilepsy (Lafora body form). I. Isolation and preliminary characterization of Lafora bodies in two cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Progressive myoclonus epilepsies: specific causes and diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Recent advances in the molecular basis of Lafora's progressive myoclonus epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

A novel protein tyrosine phosphatase gene is mutated in progressive myoclonus epilepsy of the Lafora type (EPM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Mutations in NHLRC1 cause progressive myoclonus epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Lafora progressive myoclonus epilepsy: narrowing the chromosome 6q24 locus by recombinations and homozygosities

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The gene for progressive myoclonus epilepsy of the Lafora type maps to chromosome 6q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

A unique carbohydrate binding domain targets the lafora disease phosphatase to glycogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Novel glycogen synthase kinase 3 and ubiquitination pathways in progressive myoclonus epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Epm2a suppresses tumor growth in an immunocompromised host by inhibiting Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Laforin, the dual-phosphatase responsible for Lafora disease, interacts with R5 (PTG), a regulatory subunit of protein phosphatase-1 that enhances glycogen accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Overexpression of protein targeting to glycogen (PTG) in rat hepatocytes causes profound activation of glycogen synthesis independent of normal hormone- and substrate-mediated regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Relationship between glycogen accumulation and the laforin dual specificity phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Dimerization of Laforin is required for its optimal phosphatase activity, regulation of GSK3beta phosphorylation, and Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Glycogen metabolism in tissues from a mouse model of Lafora disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Skin biopsy in Lafora disease: genotype-phenotype correlations and diagnostic pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The AMP-activated protein kinase cascade--a unifying system for energy control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

AMPK: a key sensor of fuel and energy status in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

AMP-activated protein kinase--development of the energy sensor concept.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The regulation of AMP-activated protein kinase by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Characterization of Gac1p, a regulatory subunit of protein phosphatase type I involved in glycogen accumulation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Control of glycogen deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Glycogen and its Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

The glycogenic action of protein targeting to glycogen in hepatocytes involves multiple mechanisms including phosphorylase inactivation and glycogen synthase translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Brain glycogen re-awakened

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Transcriptional profiling of a mouse model for Lafora disease reveals dysregulation of genes involved in the expression and modification of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR--an activator of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Identification of a novel protein interacting with laforin, the EPM2a progressive myoclonus epilepsy gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

TRIP6 transcriptional co-activator is a novel substrate of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Glucose-regulated interaction of a regulatory subunit of protein phosphatase 1 with the Snf1 protein kinase in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

Glycogen synthase: a new activity ratio assay expressing a high sensitivity to the phosphorylation state

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM339

21 January 2018

Identifiers

DOI

10.1093/HMG/DDM339

1 reference

16 September 2017

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