HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background (Q40068344)

17 September 2017

HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background (English)

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17 September 2017

P Massimi

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17 September 2017

A Shai

series ordinal

2

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17 September 2017

P Lambert

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3

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17 September 2017

L Banks

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4

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17 September 2017

language of work or name

English

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publication date

15 October 2007

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17 September 2017

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17 September 2017

27

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12

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17 September 2017

1800-1804

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210810

17 September 2017

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cites work

Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6.

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Requirement of E6AP and the features of human papillomavirus E6 necessary to support degradation of p53

21 January 2018

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Comparison of human papillomavirus type 18 (HPV-18) E6-mediated degradation of p53 in vitro and in vivo reveals significant differences based on p53 structure and cell type but little difference with respect to mutants of HPV-18 E6.

21 January 2018

1 reference

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Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

21 January 2018

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Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins

21 January 2018

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Degradation of hDlg and MAGIs by human papillomavirus E6 is E6-AP-independent

21 January 2018

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Growth suppression induced by downregulation of E6-AP expression in human papillomavirus-positive cancer cell lines depends on p53

21 January 2018

1 reference

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Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

21 January 2018

1 reference

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Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

21 January 2018

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The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase

21 January 2018

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Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

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Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells

21 January 2018

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Role of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31

21 January 2018

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Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins

21 January 2018

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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

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Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

21 January 2018

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Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

21 January 2018

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The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo

21 January 2018

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

21 January 2018

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

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The human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities

21 January 2018

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PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

Two polymorphic variants of wild-type p53 differ biochemically and biologically

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

The role of the E6-p53 interaction in the molecular pathogenesis of HPV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

Papillomavirus infections--a major cause of human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210810

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210810

1 reference

Dimensions Publication ID

17 September 2017

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1 reference