FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells (Q40081796)

17 September 2017

FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells (English)

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17 September 2017

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acute myeloid leukemia

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8

L Neckers

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17 September 2017

9

J B Trepel

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17 September 2017

T Kajiguchi

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17 September 2017

E J Chung

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17 September 2017

S Lee

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17 September 2017

A Stine

4

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17 September 2017

H Kiyoi

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17 September 2017

T Naoe

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17 September 2017

M J Levis

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17 September 2017

13 September 2007

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21

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2476-2484

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2404923

17 September 2017

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cites work

Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Molecular evolution of acute myeloid leukaemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Linking colorectal cancer to Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Catenins, Wnt signaling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

beta-catenin is a target for the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Regulation of beta-catenin structure and activity by tyrosine phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Vascular endothelial growth factor expression, beta-catenin tyrosine phosphorylation, and endothelial proliferative behavior: a pathway for transformation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Decisions, decisions: beta-catenin chooses between adhesion and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to alpha-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

inferred from DOI database lookup

7 January 2021

based on heuristic

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

inferred from DOI database lookup

7 January 2021

based on heuristic

The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404923

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.LEU.2404923

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Dimensions Publication ID

17 September 2017

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1 reference