Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. (Q40094640)

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24 February 2020

title

Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function (English)

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24 February 2020

Fusarium graminearum

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3

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24 February 2020

Martin Urban

2

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24 February 2020

Kim Hammond-Kosack

6

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24 February 2020

Bart A Fraaije

7

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24 February 2020

author name string

Jieru Fan

1

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24 February 2020

Helen C Brewer

4

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24 February 2020

Steven L Kelly

5

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24 February 2020

Xili Liu

8

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24 February 2020

Hans J Cools

9

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language of work or name

English

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publication date

27 February 2013

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24 February 2020

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24 February 2020

volume

198

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24 February 2020

issue

3

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24 February 2020

page(s)

821-835

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Ergosterol biosynthesis pathway in Aspergillus fumigatus.

24 February 2020

cites work

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Hydrogen peroxide induced by the fungicide prothioconazole triggers deoxynivalenol (DON) production by Fusarium graminearum

21 January 2018

1 reference

Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides

21 January 2018

1 reference

Development of a novel multiplex DNA microarray for Fusarium graminearum and analysis of azole fungicide responses

21 January 2018

1 reference

Impact of recently emerged sterol 14{alpha}-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity

21 January 2018

1 reference

Heterologous expression of mutated eburicol 14alpha-demethylase (CYP51) proteins of Mycosphaerella graminicola to assess effects on azole fungicide sensitivity and intrinsic protein function

21 January 2018

1 reference

The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization

21 January 2018

1 reference

Fusarium graminearum gene deletion mutants map1 and tri5 reveal similarities and differences in the pathogenicity requirements to cause disease on Arabidopsis and wheat floral tissue

21 January 2018

1 reference

A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus

21 January 2018

1 reference

The CYP51C gene, a reliable marker to resolve interspecific phylogenetic relationships within the Fusarium species complex and a novel target for species-specific PCR.

21 January 2018

1 reference

A novel substitution I381V in the sterol 14alpha-demethylase (CYP51) of Mycosphaerella graminicola is differentially selected by azole fungicides

21 January 2018

1 reference

Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility

21 January 2018

1 reference

Amphotericin primarily kills yeast by simply binding ergosterol

21 January 2018

1 reference

Tandem repeat of a transcriptional enhancer upstream of the sterol 14alpha-demethylase gene (CYP51) in Penicillium digitatum

21 January 2018

1 reference

Investigation of the potential for triterpene synthesis in rice through genome mining and metabolic engineering.

21 January 2018

1 reference

Molecular genetic analysis of azole antifungal mode of action

21 January 2018

1 reference

Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol.

21 January 2018

1 reference

Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea

21 January 2018

1 reference

Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms

21 January 2018

1 reference

Structural basis for conservation in the CYP51 family

21 January 2018

1 reference

Gene transcription profiling of Fusarium graminearum treated with an azole fungicide tebuconazole

21 January 2018

1 reference

Paralogous cyp51 genes in Fusarium graminearum mediate differential sensitivity to sterol demethylation inhibitors.

21 January 2018

1 reference

Identification and characterization of four azole-resistant erg3 mutants of Candida albicans

21 January 2018

1 reference

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.

21 January 2018

1 reference

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

21 January 2018

1 reference

Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.

21 January 2018

1 reference

Tri6 is a global transcription regulator in the phytopathogen Fusarium graminearum

21 January 2018

1 reference

Real-time PCR for quantification of eleven individual Fusarium species in cereals.

21 January 2018

1 reference

The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450).

21 January 2018

1 reference

Fusarium infections in immunocompromised patients

21 January 2018

1 reference

Genetically engineered Fusarium as a tool to evaluate the effects of environmental factors on initiation of trichothecene biosynthesis.

21 January 2018

1 reference

Biochemical and physiological effects of sterol alterations in yeast--a review

21 January 2018

1 reference

Fusarium ear blight (scab) in small grain cereals?a review

21 January 2018

1 reference

Efficacy of triazole-based fungicides for fusarium head blight and deoxynivalenol control in wheat: a multivariate meta-analysis

21 January 2018

1 reference

Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients

21 January 2018

1 reference

A different function for a member of an ancient and highly conserved cytochrome P450 family: from essential sterols to plant defense.

21 January 2018

1 reference

Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans

21 January 2018

1 reference

Multiple functions for sterols in Saccharomyces cerevisiae.

21 January 2018

1 reference

The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family.

21 January 2018

1 reference

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

21 January 2018

1 reference

Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

21 January 2018

1 reference

Ejection mechanics and trajectory of the ascospores of Gibberella zeae (anamorph Fuarium graminearum).

21 January 2018

1 reference

Arabidopsis is susceptible to the cereal ear blight fungal pathogens Fusarium graminearum and Fusarium culmorum.

21 January 2018

1 reference

The Fusarium graminearum MAP1 gene is essential for pathogenicity and development of perithecia

21 January 2018

1 reference

S-Adenosyl-L-methionine inhibitors delta(24)-sterol methyltransferase and delta(24(28))-sterol methylreductase as possible agents against Paracoccidioides brasiliensis

21 January 2018

1 reference

Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.

21 January 2018

1 reference

Phylogenetic distribution of fungal sterols

21 January 2018

1 reference

Sequence variation in the CYP51 gene of Blumeria graminis associated with resistance to sterol demethylase inhibiting fungicides

21 January 2018

1 reference

A sterol 14α-demethylase is required for conidiation, virulence and for mediating sensitivity to sterol demethylation inhibitors by the rice blast fungus Magnaporthe oryzae

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/NPH.12193

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24 February 2020

Fatcat ID

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Fatcat

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24 November 2022

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