Effective treatment of leukemic cell lines with wt1 siRNA. (Q40095623)

17 September 2017

Effective treatment of leukemic cell lines with wt1 siRNA. (English)

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17 September 2017

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U Koehl

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author name string

W Glienke

1

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17 September 2017

L Maute

2

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17 September 2017

R Esser

4

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17 September 2017

E Milz

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17 September 2017

L Bergmann

6

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17 September 2017

9 August 2007

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17 September 2017

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17 September 2017

21

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10

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17 September 2017

2164-2170

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2404878

17 September 2017

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The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor

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Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

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Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma.

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Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer.

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Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma

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Ribozyme-mediated cleavage of wt1 transcripts suppresses growth of leukemia cells

21 January 2018

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p53 may mediate the mdr-1 expression via the WT1 gene in human vincristine-resistant leukemia/lymphoma cell lines.

21 January 2018

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Overexpression of murine WT1 + / + and - / - isoforms has no effect on chemoresistance but delays differentiation in the K562 leukemia cell line

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Significant correlation between the degree of WT1 expression and the International Prognostic Scoring System Score in patients with myelodysplastic syndromes.

21 January 2018

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Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity.

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Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

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Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines

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Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment

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Antisense and nonantisense effects of antisense Bcl-2 on multiple roles of Bcl-2 as a chemosensitizer in cancer therapy

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Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies

21 January 2018

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Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation.

21 January 2018

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The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene

21 January 2018

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7 January 2021

Autoregulation of the human WT1 gene promoter

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Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers

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Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas

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The Wilms' tumor gene is frequently expressed in acute myeloblastic leukemias and may provide a marker for residual blast cells detectable by PCR

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7 January 2021

Suppression of Wilms' tumor gene (WT1) expression induces G2/M arrest in leukemic cells

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7 January 2021

Fluorescent 5'-exonuclease assay for the absolute quantification of Wilms' tumour gene (WT1) mRNA: implications for monitoring human leukaemias

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7 January 2021

The coexpression of the apoptosis-related genes bcl-2 and wt1 in predicting survival in adult acute myeloid leukemia

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404878

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Dimensions Publication ID

17 September 2017

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