Signal sequences for targeting of gene therapy products to subcellular compartments: the role of CRM1 in nucleocytoplasmic shuttling of the protein switch (Q40121256)

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English	Signal sequences for targeting of gene therapy products to subcellular compartments: the role of CRM1 in nucleocytoplasmic shuttling of the protein switch	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 September 2017

Signal sequences for targeting of gene therapy products to subcellular compartments: the role of CRM1 in nucleocytoplasmic shuttling of the protein switch (English)

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Europe PubMed Central

PubMed publication ID

17 September 2017

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author name string

Mudit Kakar

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Amy B Cadwallader

2

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Europe PubMed Central

PubMed publication ID

17 September 2017

James R Davis

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Carol S Lim

4

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Europe PubMed Central

PubMed publication ID

17 September 2017

language of work or name

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publication date

13 June 2007

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Europe PubMed Central

PubMed publication ID

17 September 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

17 September 2017

24

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Europe PubMed Central

PubMed publication ID

17 September 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

2146-2155

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Europe PubMed Central

PubMed publication ID

17 September 2017

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

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https://api.crossref.org/works/10.1007%2FS11095-007-9333-1

21 January 2018

Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells

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https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variants of the carboxyl-terminal KDEL sequence direct intracellular retention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

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https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleocytoplasmic transport: the soluble phase

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https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wilson's Disease.

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https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport between the cell nucleus and the cytoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wilson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular localization and trafficking of steroid receptors

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https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separable features of the ligand-binding domain determine the differential subcellular localization and ligand-binding specificity of glucocorticoid receptor and progesterone receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NESbase version 1.0: a database of nuclear export signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial mislocalization and altered assembly of a cluster of Barth syndrome mutant tafazzins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A regulatory system for use in gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional on/off switch for controlled targeting of proteins to subcellular compartments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear trafficking and gene targeting by members of the steroid/nuclear receptor superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential localization and activity of the A- and B-forms of the human progesterone receptor using green fluorescent protein chimeras

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid receptor interactions with heat shock protein and immunophilin chaperones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A C-terminal signal prevents secretion of luminal ER proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trafficking of nuclear receptors in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Creation of "super" glucocorticoid receptors by point mutations in the steroid binding domain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

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Signals mediating nuclear targeting and their regulation: application in drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeti

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model system to study classical nuclear export signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tat peptide-mediated cellular delivery: back to basics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and prediction of leucine-rich nuclear export signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlling protein compartmentalization to overcome disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NXT1 is necessary for the terminal step of Crm1-mediated nuclear export

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB in cancer: from innocent bystander to major culprit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear export signal-dependent localization of oligonucleopeptides enhances the inhibition of the protein expression from a gene transcribed in cytosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Geldanamycin, an inhibitor of Hsp90, blocks cytoplasmic retention of progesterone receptors and glucocorticoid receptors via their respective ligand binding domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signals for sorting of transmembrane proteins to endosomes and lysosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Creation and discovery of ligand-receptor pairs for transcriptional control with small molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimizing the protein switch: altering nuclear import and export signals, and ligand binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissection of a nuclear localization signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of nucleolus localization signal of betanodavirus GGNNV protein alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

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Günter Blobel--still passionate after all these years

1 reference

https://pubmed.ncbi.nlm.nih.gov/17562146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-007-9333-1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ResearchGate publication ID

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