Desensitization and binding properties determine distinct alpha1beta2gamma2 and alpha3beta2gamma2 GABA(A) receptor-channel kinetic behavior. (Q40121288)

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31 December 2019

title

Desensitization and binding properties determine distinct alpha1beta2gamma2 and alpha3beta2gamma2 GABA(A) receptor-channel kinetic behavior (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17561840%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

2

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31 December 2019

Stefano Vicini

series ordinal

4

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31 December 2019

author name string

Andrea Barberis

series ordinal

1

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31 December 2019

Pavel I Ortinski

series ordinal

3

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31 December 2019

language of work or name

English

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publication date

1 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17561840%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Neuroscience

31 December 2019

published in

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31 December 2019

volume

25

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31 December 2019

issue

9

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31 December 2019

page(s)

2726-2740

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A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction

31 December 2019

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Dynamism of GABA(A) receptor activation shapes the "personality" of inhibitory synapses.

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Four amino acids in the alpha subunits determine the gamma-aminobutyric acid sensitivities of GABAA receptor subtypes

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22 September 2017

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GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery?

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

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Defining affinity with the GABAA receptor.

22 September 2017

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Activation and deactivation rates of recombinant GABA(A) receptor channels are dependent on alpha-subunit isoform

22 September 2017

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Neuron-specific expression of GABAA-receptor subtypes: differential association of the alpha 1- and alpha 3-subunits with serotonergic and GABAergic neurons

22 September 2017

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High-efficiency transformation of mammalian cells by plasmid DNA

22 September 2017

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Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

22 September 2017

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Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors.

22 September 2017

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Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function.

25 September 2017

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Receptor system response kinetics reveal functional subtypes of native murine and recombinant human GABAA receptors

25 September 2017

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Classic benzodiazepines modulate the open-close equilibrium in alpha1beta2gamma2L gamma-aminobutyric acid type A receptors

25 September 2017

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Expression of distinct alpha subunits of GABAA receptor regulates inhibitory synaptic strength

15 June 2018

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GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

15 June 2018

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Formation of heteromeric gamma-aminobutyric acid type A receptors containing two different alpha subunits.

15 June 2018

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Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

15 June 2018

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Developmental changes of GABA synaptic transient in cerebellar granule cells

15 June 2018

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Modulation of GABA(A) receptors by hydrogen ions reveals synaptic GABA transient and a crucial role of the desensitization process.

20 August 2018

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Kinetic and pharmacological properties of GABA(A) receptors in single thalamic neurons and GABA(A) subunit expression

20 August 2018

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Developmental change in GABAA receptor desensitization kinetics and its role in synapse function in rat cortical neurons.

20 August 2018

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Changes in intracellular calcium concentration affect desensitization of GABAA receptors in acutely dissociated P2-P6 rat hippocampal neurons.

20 August 2018

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Dependence of the GABAA receptor gating kinetics on the alpha-subunit isoform: implications for structure-function relations and synaptic transmission.

20 August 2018

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20 August 2018

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Desensitized states prolong GABAA channel responses to brief agonist pulses.

20 August 2018

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Slow desensitization regulates the availability of synaptic GABA(A) receptors

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12 December 2020

Binding sites, singly bound states, and conformation coupling shape GABA-evoked currents

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12 December 2020

Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture

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12 December 2020

Transmitter timecourse in the synaptic cleft: its role in central synaptic function

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12 December 2020

10.1111/J.1460-9568.2007.05530.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17561840%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17561840%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

17561840

1 reference