Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB. (Q40139344)

17 September 2017

Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB. (English)

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17 September 2017

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Suparna Qanungo

1

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17 September 2017

David W Starke

2

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17 September 2017

Harish V Pai

3

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17 September 2017

John J Mieyal

4

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17 September 2017

Anna-Liisa Nieminen

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17 September 2017

language of work or name

English

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publication date

27 April 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

18427-18436

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17 September 2017

25

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Hypoxia and anemia: effects on tumor biology and treatment resistance

17 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M610934200

Hypoxia/reoxygenation differentially modulates NF-kappaB activation and iNOS expression in astrocytes and microglia.

21 January 2018

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N-Acetyl-L-cysteine enhances apoptosis through inhibition of nuclear factor-kappaB in hypoxic murine embryonic fibroblasts

21 January 2018

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NF-kappaB at the crossroads of life and death

21 January 2018

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Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus

21 January 2018

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Targeting NF-kappaB in hematologic malignancies

21 January 2018

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NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

21 January 2018

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Structure and mechanism in NF-kappa B/I kappa B signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M610934200

Structure of NF-kappa B p50 homodimer bound to a kappa B site

21 January 2018

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The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site

21 January 2018

1 reference

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Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress

21 January 2018

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Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M610934200

Redox modifications of protein-thiols: emerging roles in cell signaling.

21 January 2018

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Glutaredoxin: role in reversible protein s-glutathionylation and regulation of redox signal transduction and protein translocation

21 January 2018

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Oxidoreduction of protein thiols in redox regulation.

21 January 2018

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Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction

21 January 2018

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Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity

21 January 2018

1 reference

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Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.

21 January 2018

1 reference

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Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis.

21 January 2018

1 reference

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2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells

21 January 2018

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Inhibitory action of novel aromatic diamine compound on lipopolysaccharide-induced nuclear translocation of NF-kappaB without affecting IkappaB degradation

21 January 2018

1 reference

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Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status

21 January 2018

1 reference

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S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase: role of thiol oxidation and catalysis by glutaredoxin

21 January 2018

1 reference

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Regulation of cAMP-dependent protein kinase activity by glutathionylation.

21 January 2018

1 reference

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N-Acetyl-L-cysteine and pyrrolidine dithiocarbamate inhibited nuclear factor-kappaB activation in alveolar macrophages by different mechanisms.

21 January 2018

1 reference

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NFkappaB-dependent signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M610934200

Free radicals, metals and antioxidants in oxidative stress-induced cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M610934200

Cellular and molecular targets of protein S-glutathiolation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M610934200

Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells

21 January 2018

1 reference

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beta-D-Glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor kappaB but potentiates apoptosis

21 January 2018

1 reference

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Role of vicinal protein thiols in radiation and cytotoxic responses

21 January 2018

1 reference

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Thiol/disulfide exchange equilibria and disulfide bond stability

21 January 2018

1 reference

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Recent trends in glutathione biochemistry--glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation?

21 January 2018

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Neuroprotective properties of nitric oxide

21 January 2018

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Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms

21 January 2018

1 reference

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Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M610934200

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17 September 2017

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