Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition (Q40141950)

15 June 2018

title

Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition (English)

1 reference

15 June 2018

membrane fusion involved in viral entry into host cell

main subject

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author name string

Xiaohui Ding

1

1 reference

15 June 2018

Xiujuan Zhang

2

1 reference

15 June 2018

Huihui Chong

3

1 reference

15 June 2018

Yuanmei Zhu

4

1 reference

15 June 2018

Huamian Wei

5

1 reference

15 June 2018

Xiyuan Wu

6

1 reference

15 June 2018

Jinsheng He

7

1 reference

15 June 2018

Xinquan Wang

8

1 reference

15 June 2018

Yuxian He

9

1 reference

15 June 2018

language of work or name

English

0 references

publication date

24 August 2017

1 reference

15 June 2018

published in

Journal of Virology

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15 June 2018

volume

91

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15 June 2018

issue

18

1 reference

15 June 2018

A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity

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17 June 2018

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Two M-T hook residues greatly improve the antiviral activity and resistance profile of the HIV-1 fusion inhibitor SC29EK.

17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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The M-T Hook Structure Is Critical for Design of HIV-1 Fusion Inhibitors

17 June 2018

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17 June 2018

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Discovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion Inhibitor CP621-652

17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain.

17 June 2018

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HIV-1 fusion inhibitor peptides enfuvirtide and T-1249 interact with erythrocyte and lymphocyte membranes

17 June 2018

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17 June 2018

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17 June 2018

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Combinations of the first and next generations of human immunodeficiency virus (HIV) fusion inhibitors exhibit a highly potent synergistic effect against enfuvirtide- sensitive and -resistant HIV type 1 strains

17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

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17 June 2018

1 reference

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17 June 2018

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HIV entry and its inhibition

17 June 2018

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17 June 2018

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Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41

17 June 2018

1 reference

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Atomic structure of a thermostable subdomain of HIV-1 gp41

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5571253

Atomic structure of the ectodomain from HIV-1 gp41

17 June 2018

1 reference

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17 June 2018

1 reference

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17 June 2018

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Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

17 June 2018

1 reference

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17 June 2018

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17 June 2018

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Structurally altered peptides reveal an important role for N-terminal heptad repeat binding and stability in the inhibitory action of HIV-1 peptide DP178.

20 August 2018

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Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

20 August 2018

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20 August 2018

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20 August 2018

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A trimeric structural subdomain of the HIV-1 transmembrane glycoprotein

2 December 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/28659478

12 December 2020

inferred from PubMed ID database lookup

An inducible HIV type 1 gp41 HR-2 peptide-binding site on HIV type 1 envelope gp120

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28659478

12 December 2020

inferred from PubMed ID database lookup

Demonstrating the C-terminal boundary of the HIV 1 fusion conformation in a dynamic ongoing fusion process and implication for fusion inhibition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28659478

12 December 2020

inferred from PubMed ID database lookup

Identifiers

1 reference

https://api.fatcat.wiki/v0/release/tzti3mhhxzhf3gn6dtkaiarv2a

30 July 2022

release_tzti3mhhxzhf3gn6dtkaiarv2a

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tzti3mhhxzhf3gn6dtkaiarv2a

30 July 2022

https://api.fatcat.wiki/v0/release/tzti3mhhxzhf3gn6dtkaiarv2a

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/tzti3mhhxzhf3gn6dtkaiarv2a

PubMed publication ID

1 reference

30 July 2022