Seizure suppression by GDNF gene therapy in animal models of epilepsy (Q40154016)

18 September 2017

Seizure suppression by GDNF gene therapy in animal models of epilepsy (English)

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18 September 2017

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Irene Kanter-Schlifke

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18 September 2017

Biljana Georgievska

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18 September 2017

Deniz Kirik

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18 September 2017

Merab Kokaia

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18 September 2017

27 March 2007

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15

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6

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18 September 2017

1106-1113

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Characterization of a multicomponent receptor for GDNF.

18 September 2017

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo

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7 January 2021

GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

GDNF enhances the synaptic efficacy of dopaminergic neurons in culture

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7 January 2021

Ca(2+) binding protein frequenin mediates GDNF-induced potentiation of Ca(2+) channels and transmitter release

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Dopaminergic neurons protected from degeneration by GDNF gene therapy

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7 January 2021

HSV amplicon delivery of glial cell line-derived neurotrophic factor is neuroprotective against ischemic injury.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Time course of transient expression of GDNF protein in rat granule cells of the bilateral dentate gyri after unilateral intrahippocampal kainic acid injection

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Glial cell-line derived neurotrophic factor (GDNF) mRNA upregulation in striatum and cortical areas after pilocarpine-induced status epilepticus in rats

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

The messenger RNAs for both glial cell line-derived neurotrophic factor receptors, c-ret and GDNFRalpha, are induced in the rat brain in response to kainate-induced excitation.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

GDNF family ligands and receptors are differentially regulated after brain insults in the rat.

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7 January 2021

Potent inhibitory effects of glial derived neurotrophic factor against kainic acid mediated seizures in the rat.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Glial cell line-derived neurotrophic factor modulates kindling and activation-induced sprouting in hippocampus of adult rats

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Neuroprotection of adenoviral-vector-mediated GDNF expression against kainic-acid-induced excitotoxicity in the rat hippocampus

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Gene transfer into neurons from hippocampal slices: comparison of recombinant Semliki Forest Virus, adenovirus, adeno-associated virus, lentivirus, and measles virus.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Overexpression of neuropeptide Y induced by brain-derived neurotrophic factor in the rat hippocampus is long lasting

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes

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7 January 2021

Suppressed epileptogenesis in BDNF mutant mice

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7 January 2021

Spontaneous limbic seizures after intrahippocampal infusion of brain-derived neurotrophic factor.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Modification of seizure activity by electrical stimulation. I. After-discharge threshold.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Ret, GFRalpha-1, GFRalpha-2 and GFRalpha-3 receptors in the human hippocampus and fascia dentata.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Localization of GDNF/neurturin receptor (c-ret, GFRalpha-1 and alpha-2) mRNAs in postnatal rat brain: differential regional and temporal expression in hippocampus, cortex and cerebellum

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

GDNF pre-treatment aggravates neuronal cell loss in oxygen–glucose deprived hippocampal slice cultures: a possible effect of glutamate transporter up-regulation

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Seizure-induced glutamate release in mature and immature animals: an in vivo microdialysis study.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Extracellular concentrations of amino acid transmitters in ventral hippocampus during and after the development of kindling.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Regulation of quantal secretion by neurotrophic factors at developing motoneurons in Xenopus cell cultures.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Differential effects of GDNF and BDNF on cultured ventral mesencephalic neurons

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

GDNF acutely potentiates Ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Afferent-specific modulation of short-term synaptic plasticity by neurotrophins in dentate gyrus

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Endogenous neurotrophin-3 regulates short-term plasticity at lateral perforant path-granule cell synapses.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor alpha 2.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Recombinant adeno-associated virus serotypes 2- and 5-mediated gene transfer in the mammalian brain: quantitative analysis of heparin co-infusion

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Modification of seizure activity by electrical stimulation. II. Motor seizure

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300148

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300148

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18 September 2017

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