Overcoming tumor drug resistance with high-affinity taxanes: a SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines. (Q40154203)

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28 December 2019

title

Overcoming tumor drug resistance with high-affinity taxanes: a SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines (English)

1 reference

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28 December 2019

6

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28 December 2019

J. Fernando Díaz

8

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28 December 2019

Wei-Shuo Fang

9

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28 December 2019

author name string

Chun-Gang Yang

1

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28 December 2019

Isabel Barasoain

2

1 reference

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28 December 2019

Xuan Li

3

1 reference

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28 December 2019

Ruth Matesanz

4

1 reference

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28 December 2019

Ronghua Liu

5

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28 December 2019

Da-Li Yin

7

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28 December 2019

publication date

1 May 2007

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28 December 2019

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28 December 2019

volume

2

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28 December 2019

issue

5

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28 December 2019

page(s)

691-701

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A systematic SAR study of C10 modified paclitaxel analogues using a combinatorial approach

28 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Taxol, a molecule for all seasons

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

General and recent aspects of the chemistry and structure-activity relationships of taxoids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 3.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and antitumor activity of novel C-7 paclitaxel ethers: discovery of BMS-184476.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and evaluation of paclitaxel C7 derivatives: solution phase synthesis of combinatorial libraries

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Modulation of multidrug resistance by taxuspine C and other taxoids from Japanese yew

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

New highly active taxoids from 9 beta-dihydrobaccatin-9,10-acetals

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and cytotoxicity of 2alpha-amido docetaxel analogues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and biological evaluation of 2-acyl analogues of paclitaxel (Taxol).

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Efficient Asymmetric Syntheses of β-Lactams Bearing a Cyclopropane or an Epoxide Moiety and Their Application to the Syntheses of Novel Isoserines and Taxoids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Structure-activity relationships study at the 3'-N position of paclitaxel. Part 2: synthesis and biological evaluation of 3'-N-thiourea- and 3'-N-thiocarbamate-bearing paclitaxel analogues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Structure–activity relationship study at the 3′-N-position of paclitaxel: synthesis and biological evaluation of 3′-N-acyl-paclitaxel analogues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and structure-activity relationships of new second-generation taxoids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and biological evaluation of C-3'NH/C-10 and C-2/C-10 modified paclitaxel analogues.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Antileukemic alkaloids from Taxus wallichiana Zucc

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and separation of potential anticancer active dihalocephalomannine diastereomers from extracts of Taxus yunnanensis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Unexpectedly Facile Hydrolysis of the 2-Benzoate Group of Taxol and Syntheses of Analogs with Increased Activities

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and Structure−Activity Relationships of Nonaromatic Taxoids: Effects of Alkyl and Alkenyl Ester Groups on Cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Synthesis and Biological Evaluation of 2-epi-Paclitaxel.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Thermodynamics of ligand-induced assembly of tubulin.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Do beta-tubulin mutations have a role in resistance to chemotherapy?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

The interaction of baccatin III with the taxol binding site of microtubules determined by a homogeneous assay with fluorescent taxoid

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Fast kinetics of Taxol binding to microtubules. Effects of solution variables and microtubule-associated proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021

Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700002

7 January 2021