Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development (Q24292104)

IRE1-mediated unfolded protein response

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Endoplasmic reticulum chaperone BiP homolog;Heat shock 70 kDa protein D CELE_F43E2.8

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Serine/threonine-protein kinase CELE_C41C4.4

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Heat shock 70 kDa protein C CELE_C15H9.6

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Eukaryotic translation initiation factor 2-alpha kinase pek-1 CELE_F46C3.1

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H Yoshida

7

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author name string

X Shen

1

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R E Ellis

2

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K Lee

3

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C Y Liu

4

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K Yang

5

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A Solomon

6

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R Morimoto

8

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D M Kurnit

9

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K Mori

10

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R J Kaufman

Integration of endoplasmic reticulum signaling in health and disease

11

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language of work or name

English

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publication date

28 December 2001

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published in

Cell

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volume

107

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page(s)

893-903

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issue

7

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cites work

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7 January 2021

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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7 January 2021

Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

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7 January 2021

A novel member of the tob family of proteins controls sexual fate in Caenorhabditis elegans germ cells

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7 January 2021

Translational attenuation mediated by an mRNA intron

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7 January 2021

The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core

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7 January 2021

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

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7 January 2021

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

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7 January 2021

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

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7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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7 January 2021

Neuropathology of degenerative cell death in Caenorhabditis elegans

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7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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7 January 2021

Perk is essential for translational regulation and cell survival during the unfolded protein response

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7 January 2021

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

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7 January 2021

Real time quantitative PCR

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7 January 2021

Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress

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7 January 2021

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun.

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7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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7 January 2021

Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response

1 reference

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7 January 2021

Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response

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7 January 2021

A comparison of the different DNA binding specificities of the bZip proteins C/EBP and GCN4.

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7 January 2021

Conformational disease

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7 January 2021

Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.

1 reference

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7 January 2021

Targeted disruption of CRE-binding factor TREB5 gene leads to cellular necrosis in cardiac myocytes at the embryonic stage

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7 January 2021

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

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7 January 2021

Tripartite management of unfolded proteins in the endoplasmic reticulum

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7 January 2021

mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response

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7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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7 January 2021

IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae

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7 January 2021

Plasma cell differentiation requires the transcription factor XBP-1

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7 January 2021

Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response

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7 January 2021

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

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7 January 2021

The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast

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7 January 2021

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

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7 January 2021

tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

1 reference

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7 January 2021

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

1 reference

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7 January 2021

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

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7 January 2021

The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

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7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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7 January 2021

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

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7 January 2021

Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum

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7 January 2021

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

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7 January 2021

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

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7 January 2021

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

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7 January 2021

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

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7 January 2021

Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response

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7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

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7 January 2021

10.1016/S0092-8674(01)00612-2

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

496117

496117

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference