A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis (Q40167332)

18 September 2017

A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis (English)

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18 September 2017

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viral rna synthesis

13 November 2022

influenza A virus

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Ji-Young Min

1

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18 September 2017

Shoudong Li

series ordinal

2

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18 September 2017

Ganes C Sen

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3

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18 September 2017

Robert M Krug

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4

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18 September 2017

language of work or name

English

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publication date

22 February 2007

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18 September 2017

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18 September 2017

363

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18 September 2017

236-243

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18 September 2017

1

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X-ray structure of influenza virus NS1 effector domain

18 September 2017

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

7 January 2021

1 reference

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Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode

7 January 2021

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Interaction of influenza virus NS1 protein and the human homologue of Staufen in vivo and in vitro

7 January 2021

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Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 protein

7 January 2021

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Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

7 January 2021

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Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses

7 January 2021

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Binding and nuclear relocalization of protein kinase R by human cytomegalovirus TRS1.

7 January 2021

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Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Binding of influenza A virus NS1 protein to dsRNA in vitro

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The double stranded RNA-activated protein kinase induced by interferon: dsRNA-PK.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein

7 January 2021

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Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs

7 January 2021

1 reference

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Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

7 January 2021

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The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Molecular basis for PKR activation by PACT or dsRNA

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor

7 January 2021

1 reference

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Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivo

7 January 2021

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The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The influenza virus NS1 protein forms multimers in vitro and in vivo

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

PACT, a protein activator of the interferon-induced protein kinase, PKR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Extragenic suppression of temperature-sensitive mutations in RNA segment 8 by replacement of different rna segments with those of other influenza A virus prototype strains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Regulation of influenza virus RNA polymerase activity by cellular and viral factors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Early polypeptide synthesis in influenza virus-infected cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The RNA-binding and effector domains of the viral NS1 protein are conserved to different extents among influenza A and B viruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Identification and requirement of three ribosome binding domains in dsRNA-dependent protein kinase (PKR).

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

inferred from DOI database lookup

7 January 2021

based on heuristic

Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.01.038

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2007.01.038

1 reference

18 September 2017

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