Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis (Q40191484)

18 September 2017

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis (English)

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18 September 2017

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John Ridgway

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Gregory D. Plowman

object named as

Greg Plowman

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author name string

John Ridgway

1

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18 September 2017

Gu Zhang

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18 September 2017

Yan Wu

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18 September 2017

Scott Stawicki

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18 September 2017

Wei-Ching Liang

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18 September 2017

Yvan Chanthery

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18 September 2017

Joe Kowalski

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18 September 2017

Ryan J Watts

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18 September 2017

Christopher Callahan

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18 September 2017

Ian Kasman

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18 September 2017

Mallika Singh

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18 September 2017

May Chien

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18 September 2017

Christine Tan

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18 September 2017

Jo-Anne S Hongo

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18 September 2017

Fred de Sauvage

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18 September 2017

Minhong Yan

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18 September 2017

language of work or name

English

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publication date

1 December 2006

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18 September 2017

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18 September 2017

444

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18 September 2017

1083-1087

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18 September 2017

7122

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https://scigraph.springernature.com/pub.10.1038/nature05313

18 September 2017

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Dosage-sensitive requirement for mouse Dll4 in artery development

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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

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Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

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7 January 2021

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

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7 January 2021

Notch signals control the fate of immature progenitor cells in the intestine

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7 January 2021

Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1.

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

An overview of the Notch signalling pathway

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

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7 January 2021

Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function

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7 January 2021

Relationship between astrocytes, ganglion cells and vasculature of the retina

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7 January 2021

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

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7 January 2021

Periodic Delta-like 4 expression in developing retinal arteries.

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

Endothelial cells and VEGF in vascular development

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7 January 2021

Angiogenesis as a therapeutic target

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https://api.crossref.org/works/10.1038%2FNATURE05313

7 January 2021

Lessons from phase III clinical trials on anti-VEGF therapy for cancer

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Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

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7 January 2021

Identifiers

DOI

10.1038/NATURE05313

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Dimensions Publication ID

18 September 2017

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1 reference