An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells (Q40193234)

18 September 2017

An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells (English)

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18 September 2017

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Davis W Cheng

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18 September 2017

Yan Jiang

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Anath Shalev

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Renu Kowluru

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Errol D Crook

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Lalit P Singh

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18 September 2017

language of work or name

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1 October 2006

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Archives of Physiology and Biochemistry

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112

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4-5

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189-218

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describes a project that uses

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SV40 MES 13

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cites work

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Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-ce

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A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase Cepsilon, and MAPK in mesangial cells regulates interferon-gamma-induced STAT1alpha transcriptional activation

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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

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Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance

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Transforming growth factor-beta1 regulation of laminin gamma1 and fibronectin expression and survival of mouse mesangial cells

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Vitamin D3 up-regulated protein-1 regulates collagen expression in mesangial cells

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High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells

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VDUP1 is required for the development of natural killer cells.

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Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells

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Hexosamine pathway is responsible for inhibition by diabetes of phenylephrine-induced inotropy

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In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats

21 January 2018

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Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein

21 January 2018

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Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

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Hexosamine-induced fibronectin protein synthesis in mesangial cells is associated with increases in cAMP responsive element binding (CREB) phosphorylation and nuclear CREB: the involvement of protein kinases A and C.

21 January 2018

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Hexosamines and TGF-β1use similar signaling pathways to mediate matrix protein synthesis in mesangial cells

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Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells.

21 January 2018

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Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway

21 January 2018

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Role of upstream stimulatory factors in regulation of renal transforming growth factor-beta1.

21 January 2018

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10.1080/13813450601093518

21 January 2018

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DOI

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18 September 2017

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