Exogenous wt-p53 enhances the antitumor effect of HSV-TK/GCV on C6 glioma cells (Q40208813)

18 September 2017

title

Exogenous wt-p53 enhances the antitumor effect of HSV-TK/GCV on C6 glioma cells (English)

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18 September 2017

Qiang Huang

1

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18 September 2017

Peiyu Pu

series ordinal

2

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18 September 2017

Zhibo Xia

series ordinal

3

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18 September 2017

Yongping You

series ordinal

4

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18 September 2017

publication date

11 November 2006

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Journal of Neuro-Oncology

18 September 2017

published in

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18 September 2017

volume

82

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18 September 2017

issue

3

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18 September 2017

page(s)

239-248

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Effective treatment of experimental glioblastoma by HSV vector-mediated TNF alpha and HSV-tk gene transfer in combination with radiosurgery and ganciclovir administration

18 September 2017

cites work

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12 December 2020

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

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12 December 2020

Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo

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12 December 2020

Perspectives for the gene therapy of malignant gliomas by suicide gene transfer

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12 December 2020

Curative potential of herpes simplex virus thymidine kinase gene transfer in rats with 9L gliosarcoma

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12 December 2020

AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

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12 December 2020

Adenovirus-mediated p53 gene transfer suppresses growth of human glioblastoma cells in vitro and in vivo

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12 December 2020

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

1 reference

12 December 2020

In vitro and in vivo antitumor effects of retrovirus-mediated herpes simplex thymidine kinase gene-transfer in human medulloblastoma

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12 December 2020

Adenovirus-mediated wild-type p53 gene transfer and overexpression induces apoptosis of human glioma cells independent of endogenous p53 status.

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12 December 2020

Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis

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12 December 2020

Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: long-term follow-up by magnetic resonance imaging

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12 December 2020

Influence of p53 status on the HSV-Tk/GCV-induced bystander effect in a panel of human ovarian carcinoma cell lines

1 reference

12 December 2020

Adenovirus-mediated gene therapy of experimental gliomas

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12 December 2020

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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12 December 2020

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

1 reference

12 December 2020

Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results

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12 December 2020

Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging

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12 December 2020

In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

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12 December 2020

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

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12 December 2020

Recombinant interleukin-2 enhanced the antitumor effect of ADV/RSV-HSV-tk/ACV therapy in a murine bladder cancer model

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12 December 2020

Efficacy of adenovirus-mediated CD/5-FC and HSV-1 thymidine kinase/ganciclovir suicide gene therapies concomitant with p53 gene therapy

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12 December 2020

Drug sensitivity ("suicide") genes for selective cancer chemotherapy.

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12 December 2020

Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions

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12 December 2020

Limited efficacy of the HSV-TK/GCV system for gene therapy of malignant gliomas and perspectives for the combined transduction of the interleukin-4 gene

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12 December 2020

Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir

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12 December 2020

Increased expression of schwannoma-derived growth factor (SDGF) mRNA in rat tumor cells: involvement of SDGF in the growth promotion of rat gliomas

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12 December 2020

The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication

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12 December 2020

Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

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12 December 2020

1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis.

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12 December 2020

Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells.

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12 December 2020

Adenovirus-mediated p53 gene transfer inhibits growth of human tumor cells expressing mutant p53 protein

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12 December 2020

Herpes simplex virus thymidine kinase gene therapy for rat malignant brain tumors

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12 December 2020

10.1007/S11060-006-9279-X

Identifiers

DOI

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Dimensions Publication ID

18 September 2017

1001605630

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