PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine (Q40211467)

18 September 2017

PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine (English)

1 reference

18 September 2017

Tiangang Li

1

1 reference

PubMed ID

17088262

18 September 2017

Wenling Chen

series ordinal

2

1 reference

PubMed ID

17088262

18 September 2017

John Y L Chiang

series ordinal

3

1 reference

18 September 2017

6 November 2006

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Journal of Lipid Research

18 September 2017

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18 September 2017

48

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18 September 2017

2

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18 September 2017

373-384

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Regulation of bile acid synthesis

18 September 2017

1 reference

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The enzymes, regulation, and genetics of bile acid synthesis

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1 reference

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Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages

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Atherosclerosis — An Inflammatory Disease

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

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Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

21 January 2018

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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

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Liver X Receptor Signaling Pathways in Cardiovascular Disease

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27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

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Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis

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Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages

21 January 2018

1 reference

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Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARgamma ligands

21 January 2018

1 reference

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The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

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Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

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CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor

21 January 2018

1 reference

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Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes

21 January 2018

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Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

21 January 2018

1 reference

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Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites

21 January 2018

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ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

21 January 2018

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Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells

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Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

21 January 2018

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Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes

21 January 2018

1 reference

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PXR and the regulation of apoA1 and HDL-cholesterol in rodents

21 January 2018

1 reference

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What is so special about apolipoprotein AI in reverse cholesterol transport?

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New insights into the regulation of HDL metabolism and reverse cholesterol transport

21 January 2018

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ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

21 January 2018

1 reference

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Transcriptional regulatory networks in lipid metabolism control ABCA1 expression

21 January 2018

1 reference

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ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I.

21 January 2018

1 reference

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Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription

21 January 2018

1 reference

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Expression of the pregnane X receptor in mice antagonizes the cholic acid-mediated changes in plasma lipoprotein profile.

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A role for the pregnane X receptor in high-density lipoprotein metabolism

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10.1194/JLR.M600282-JLR200

21 January 2018

Identifiers

DOI

1 reference

18 September 2017

1 reference

PubMed ID

17088262