The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization (Q40236645)

18 September 2017

The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization (English)

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18 September 2017

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Nai-Ying Yang

1

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18 September 2017

Elena B Pasquale

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2

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18 September 2017

Laurie B Owen

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3

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18 September 2017

Iryna M Ethell

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4

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18 September 2017

language of work or name

English

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publication date

31 August 2006

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Journal of Biological Chemistry

18 September 2017

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18 September 2017

281

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18 September 2017

43

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18 September 2017

32574-32586

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Eph receptors and ephrin ligands: embryogenesis to tumorigenesis

18 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M604338200

Novel and known protein tyrosine kinases and their abnormal expression in human melanoma

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604338200

Abnormal protein tyrosine kinase gene expression during melanoma progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Protein tyrosine kinases in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Overexpression of the EphA2 tyrosine kinase in prostate cancer.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604338200

Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604338200

Multiple redundant sequence elements within the fission yeast ura4 replication origin enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Coexpression of ephrin-Bs and their receptors in colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Inhibition of tumor growth and angiogenesis by soluble EphB4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Expression of Ephb2 and Ephb4 in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Mechanisms and functions of Eph and ephrin signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604338200

Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

An Eph receptor regulates integrin activity through R-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Role of ephrin B2 in human retinal endothelial cell proliferation and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Reciprocal expression of the Eph receptor Cek5 and its ligand(s) in the early retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphB/syndecan-2 signaling in dendritic spine morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Speculations on the Role of Ultraviolet Radiation in the Development of Malignant Melanoma4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Fas and Fas ligand interactions suppress melanoma lung metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Regulation of cancer cell motility through actin reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphB1 associates with Grb7 and regulates cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphB1-mediated cell migration requires the phosphorylation of paxillin at Tyr-31/Tyr-118.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Vav family GEFs link activated Ephs to endocytosis and axon guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Eph receptors inactivate R-Ras through different mechanisms to achieve cell repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604338200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604338200

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18 September 2017

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