Apoptin is modified by SUMO conjugation and targeted to promyelocytic leukemia protein nuclear bodies. (Q40241102)

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29 December 2019

title

Apoptin is modified by SUMO conjugation and targeted to promyelocytic leukemia protein nuclear bodies (English)

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29 December 2019

4

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29 December 2019

David A Jans

3

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29 December 2019

author name string

K Janssen

1

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29 December 2019

T G Hofmann

2

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29 December 2019

K Schulze-Osthoff

5

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29 December 2019

U Fischer

6

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29 December 2019

language of work or name

English

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publication date

21 August 2006

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29 December 2019

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29 December 2019

volume

26

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29 December 2019

issue

11

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29 December 2019

page(s)

1557-1566

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209923

29 December 2019

exact match

0 references

cites work

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Role of PML and the PML-nuclear body in the control of programmed cell death

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Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.

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SUMO regulates the cytoplasmonuclear transport of its target protein Daxx

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Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells

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Importance of nuclear localization of apoptin for tumor-specific induction of apoptosis

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PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

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Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner

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New approaches and therapeutics targeting apoptosis in disease

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Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells.

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Regulation of p53 activity in nuclear bodies by a specific PML isoform

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TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells

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Loss of the tumor suppressor PML in human cancers of multiple histologic origins

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SUMO: a history of modification

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Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

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Body language: the function of PML nuclear bodies in apoptosis regulation

21 January 2018

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The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition

21 January 2018

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Protein modification by SUMO

21 January 2018

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Identification of three major sentrinization sites in PML

21 January 2018

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Prevalent conformations and subunit exchange in the biologically active apoptin protein multimer.

21 January 2018

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Apoptin induces tumor-specific apoptosis as a globular multimer.

21 January 2018

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SUMO, ubiquitin's mysterious cousin

21 January 2018

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The tumour specific pro-apoptotic factor apoptin (Vp3) from chicken anaemia virus.

21 January 2018

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Site-directed mutagenesis of the VP2 gene of Chicken anemia virus affects virus replication, cytopathology and host-cell MHC class I expression

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The nucleoporin RanBP2 has SUMO1 E3 ligase activity

21 January 2018

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Specific tumor-cell killing with adenovirus vectors containing the apoptin gene

21 January 2018

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Apoptin nuclear accumulation is modulated by a CRM1-recognized nuclear export signal that is active in normal but not in tumor cells

21 January 2018

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A tumor cell-specific nuclear targeting signal within chicken anemia virus VP3/apoptin.

21 January 2018

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Role and fate of PML nuclear bodies in response to interferon and viral infections

21 January 2018

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SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

21 January 2018

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A tumor-specific kinase activity regulates the viral death protein Apoptin

21 January 2018

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Interaction of Daxx, a Fas binding protein, with sentrin and Ubc9

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Bcl-xL inhibits p53- but not apoptin-induced apoptosis in head and neck squamous cell carcinoma cell line

21 January 2018

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Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation

21 January 2018

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SUMO modification of Huntingtin and Huntington's disease pathology

21 January 2018

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Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

21 January 2018

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Apoptin: specific killer of tumor cells?

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Gene therapy with apoptin induces regression of xenografted human hepatomas

21 January 2018

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Role of PML in cell growth and the retinoic acid pathway

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P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2.

21 January 2018

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Differential sensitivity to Ad5 E1B-21kD and Bcl-2 proteins of apoptin-induced versus p53-induced apoptosis.

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p300 Transcriptional Repression Is Mediated by SUMO Modification

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7 January 2021

A single chicken anemia virus protein induces apoptosis

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A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture

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PML is essential for multiple apoptotic pathways

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209923

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16924230%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

0 references

1 reference