Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease (Q40242764)

18 September 2017

Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease (English)

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18 September 2017

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Anke Van der Perren

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18 September 2017

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Zeger Debyser

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Veerle Baekelandt

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Veerle Baekelandt

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18 September 2017

Linda Vercammen

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18 September 2017

Elisabetta Vaudano

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18 September 2017

Rik Gijsbers

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18 September 2017

Chris Van den Haute

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18 September 2017

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17 August 2006

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716-723

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Genetics of Parkinson disease: paradigm shifts and future prospects.

18 September 2017

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Genetics of Parkinson's disease

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Parkin genetics: one model for Parkinson's disease

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

7 January 2021

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How does parkin ligate ubiquitin to Parkinson's disease?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Parkin counteracts symptoms in a Drosophila model of Parkinson's disease

7 January 2021

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Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease

7 January 2021

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Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

7 January 2021

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Characterization of lentiviral vector-mediated gene transfer in adult mouse brain

7 January 2021

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Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

7 January 2021

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Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat.

7 January 2021

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Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

7 January 2021

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Drug-induced rotation intensity in unilateral dopamine-depleted rats is not correlated with end point or qualitative measures of forelimb or hindlimb motor performance

7 January 2021

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A novel skilled-reaching impairment in paw supination on the "good" side of the hemi-Parkinson rat improved with rehabilitation.

7 January 2021

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Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

7 January 2021

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Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

7 January 2021

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Loss of locus coeruleus neurons and reduced startle in parkin null mice

7 January 2021

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Parkin-deficient mice are not a robust model of parkinsonism

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function

7 January 2021

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Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.06.009

Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

7 January 2021

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Parkin attenuates manganese-induced dopaminergic cell death

7 January 2021

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Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

7 January 2021

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Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults

7 January 2021

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Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

7 January 2021

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Animal models of neurological deficits: how relevant is the rat?

7 January 2021

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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

7 January 2021

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6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease

7 January 2021

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Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry

7 January 2021

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Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

7 January 2021

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Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

7 January 2021

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Optimized lentiviral vector production and purification procedure prevents immune response after transduction of mouse brain

7 January 2021

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CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury

7 January 2021

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Skilled reaching an action pattern: stability in rat (Rattus norvegicus) grasping movements as a function of changing food pellet size

7 January 2021

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Design-based stereology in neuroscience

7 January 2021

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10.1016/J.YMTHE.2006.06.009

7 January 2021

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18 September 2017

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