Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway. (Q40242920)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26636256%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway (English)

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1 March 2020

4

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1 March 2020

Joseph A Newman

series ordinal

1

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1 March 2020

Christopher D. Cooper

series ordinal

2

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1 March 2020

author name string

Hazel Aitkenhead

series ordinal

3

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publication date

1 December 2015

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1 March 2020

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volume

23

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issue

12

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page(s)

2319-2330

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Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: insights from DNA complex structures

1 March 2020

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22 September 2017

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Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

22 September 2017

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22 September 2017

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22 September 2017

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Mechanism of suppression of chromosomal instability by DNA polymerase POLQ

22 September 2017

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Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

22 September 2017

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22 September 2017

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Functional characterization of UvrD helicases from Haemophilus influenzae and Helicobacter pylori

22 September 2017

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Promiscuous DNA synthesis by human DNA polymerase θ

22 September 2017

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22 September 2017

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Synthetic lethality: exploiting the addiction of cancer to DNA repair

22 September 2017

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Human HEL308 localizes to damaged replication forks and unwinds lagging strand structures

22 September 2017

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Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.

22 September 2017

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Overexpression of POLQ confers a poor prognosis in early breast cancer patients

22 September 2017

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DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

22 September 2017

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A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown

22 September 2017

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Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation

22 September 2017

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Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

22 September 2017

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Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm

22 September 2017

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Structure of the human RECQ1 helicase reveals a putative strand-separation pin

22 September 2017

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22 September 2017

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22 September 2017

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Structure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory Domains

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26636256

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2015.10.014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26636256%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26636256%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

26636256

1 reference