Rac1 mediates intestinal epithelial cell apoptosis via JNK. (Q40263028)

19 September 2017

title

Rac1 mediates intestinal epithelial cell apoptosis via JNK. (English)

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19 September 2017

Shi Jin

1

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19 September 2017

Ramesh M Ray

series ordinal

2

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19 September 2017

Leonard R Johnson

series ordinal

3

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19 September 2017

publication date

22 June 2006

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American Journal of Physiology - Gastrointestinal and Liver Physiology

19 September 2017

published in

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19 September 2017

volume

291

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19 September 2017

issue

6

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19 September 2017

page(s)

G1137-47

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Rho signals to cell growth and apoptosis

19 September 2017

cites work

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Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-alpha in IEC-6 cells

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Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activity

21 January 2018

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

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Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species

21 January 2018

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Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production

21 January 2018

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Implication of the small GTPase Rac1 in the apoptosis induced by UV in Rat-2 fibroblasts

21 January 2018

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Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway.

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21 January 2018

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Role of intestinal epithelial apoptosis in survival

21 January 2018

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Statins inhibit beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes via a Rac1-dependent mechanism.

21 January 2018

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c-Fos is a mediator of the c-myc-induced apoptotic signaling in serum-deprived hepatoma cells via the p38 mitogen-activated protein kinase pathway

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Capsaicin-induced apoptosis of H-ras-transformed human breast epithelial cells is Rac-dependent via ROS generation

21 January 2018

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Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

21 January 2018

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Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons

21 January 2018

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Role of JNK activation in apoptosis: a double-edged sword

21 January 2018

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Protein phosphatase 2A-mediated cross-talk between p38 MAPK and ERK in apoptosis of cardiac myocytes

21 January 2018

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

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Rac1 is required for cell proliferation and G2/M progression.

21 January 2018

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Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB

21 January 2018

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Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.

21 January 2018

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Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase.

21 January 2018

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Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria

21 January 2018

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Cell migration: Rho GTPases lead the way

21 January 2018

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The requirement for polyamines for intestinal epithelial cell migration is mediated through Rac1.

21 January 2018

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Polyamine depletion delays apoptosis of rat intestinal epithelial cells

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells

21 January 2018

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Resveratrol induces FasL-related apoptosis through Cdc42 activation of ASK1/JNK-dependent signaling pathway in human leukemia HL-60 cells.

21 January 2018

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Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas.

21 January 2018

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Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

21 January 2018

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A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

21 January 2018

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MEK1 restores migration of polyamine-depleted cells by retention and activation of Rac1 in the cytoplasm

21 January 2018

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Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis

21 January 2018

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Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells

21 January 2018

1 reference

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The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00031.2006

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00031.2006

Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.

21 January 2018

1 reference

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Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00031.2006

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00031.2006

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19 September 2017

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