Bortezomib induces in HepG2 cells IkappaBalpha degradation mediated by caspase-8. (Q40273993)

19 September 2017

title

Bortezomib induces in HepG2 cells IkappaBalpha degradation mediated by caspase-8. (English)

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19 September 2017

Giuseppe Calvaruso

1

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19 September 2017

Michela Giuliano

2

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19 September 2017

Patrizia Portanova

3

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19 September 2017

Anna De Blasio

4

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19 September 2017

Renza Vento

5

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19 September 2017

Giovanni Tesoriere

6

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19 September 2017

publication date

30 May 2006

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Molecular and Cellular Biochemistry

19 September 2017

published in

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19 September 2017

volume

287

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19 September 2017

issue

1-2

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19 September 2017

page(s)

13-19

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New insights into the role of nuclear factor-kB in cell growth regulation

19 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS11010-005-9016-3

Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-κB-dependent process

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A caspase-3-like protease is involved in NF-kappaB activation induced by stimulation of N-methyl-D-aspartate receptors in rat striatum

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Nuclear factor-kappa B and cancer: its role in prevention and therapy

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The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

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12 December 2020

Nuclear factor-kappaB activation mediates cellular transformation, proliferation, invasion angiogenesis and metastasis of cancer

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Maximal apoptosis of renal cell carcinoma by the proteasome inhibitor bortezomib is nuclear factor-kappaB dependent.

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pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase.

1 reference

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Bortezomib, a newly approved proteasome inhibitor for the treatment of multiple myeloma: nursing implications

1 reference

12 December 2020

Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3.

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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The proteasome as a target for cancer therapy.

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12 December 2020

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

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12 December 2020

The proteasome: a suitable antineoplastic target

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12 December 2020

Regulation of apoptosis proteins in cancer cells by ubiquitin

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12 December 2020

EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX.

1 reference

12 December 2020

Features of apoptotic cells measured by flow cytometry

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12 December 2020

Mechanisms of caspase activation

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12 December 2020

Molecular mechanisms implicated in galectin-1-induced apoptosis: activation of the AP-1 transcription factor and downregulation of Bcl-2.

1 reference

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Protective roles of NF-kB for chromium (VI)-induced cytotoxicity is revealed by expression of IkB kinase-B mutant

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The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer

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Glutamate activates NF-kappaB through calpain in neurons

1 reference

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

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Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation

1 reference

12 December 2020

IkappaB kinases: key regulators of the NF-kappaB pathway

1 reference

12 December 2020

Nuclear factor-kappaB: the enemy within

1 reference

12 December 2020

Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells

1 reference

12 December 2020

JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways.

1 reference

12 December 2020

Nuclear factor-kappaB modulation as a therapeutic approach in hematologic malignancies

1 reference

12 December 2020

The MEK/ERK pathway acts upstream of NF kappa B1 (p50) homodimer activity and Bcl-2 expression in a murine B-cell lymphoma cell line. MEK inhibition restores radiation-induced apoptosis

1 reference

12 December 2020

10.1007/S11010-005-9016-3

Identifiers

DOI

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19 September 2017

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