Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling (Q40279493)

19 September 2017

Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling (English)

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19 September 2017

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M Marderosian

1

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19 September 2017

A Sharma

2

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19 September 2017

A P Funk

3

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19 September 2017

R Vartanian

4

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19 September 2017

J Masri

5

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19 September 2017

O D Jo

6

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19 September 2017

J F Gera

7

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19 September 2017

language of work or name

English

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publication date

15 May 2006

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19 September 2017

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19 September 2017

25

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19 September 2017

47

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19 September 2017

6277-6290

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209645

19 September 2017

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The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.

21 January 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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An expanding role for mTOR in cancer

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Involvement of microRNA in AU-rich element-mediated mRNA instability

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

21 January 2018

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TOR signaling: an odyssey from cellular stress to the cell growth machinery

21 January 2018

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7 January 2021

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant

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7 January 2021

Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover

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7 January 2021

Analysis of the function, expression, and subcellular distribution of human tristetraprolin

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7 January 2021

The role of mRNA turnover in the regulation of tristetraprolin expression: evidence for an extracellular signal-regulated kinase-specific, AU-rich element-dependent, autoregulatory pathway

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7 January 2021

MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding

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7 January 2021

p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation

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7 January 2021

AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation

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7 January 2021

Mammalian TOR: a homeostatic ATP sensor

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7 January 2021

Unlocking the code of 14-3-3.

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7 January 2021

Therapeutic potential of target of rapamycin inhibitors

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7 January 2021

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

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7 January 2021

AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression

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7 January 2021

Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

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7 January 2021

Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells

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7 January 2021

Upstream and downstream of mTOR

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7 January 2021

The 14-3-3 cancer connection

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7 January 2021

mTOR as a target for cancer therapy.

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7 January 2021

Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

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7 January 2021

The mRNA closed-loop model: the function of PABP and PABP-interacting proteins in mRNA translation

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7 January 2021

Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

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7 January 2021

Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex

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7 January 2021

Influence of nonameric AU-rich tristetraprolin-binding sites on mRNA deadenylation and turnover

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7 January 2021

Regulation of c-myc mRNA decay by translational pausing in a coding region instability determinant

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7 January 2021

Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis

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7 January 2021

Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover

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7 January 2021

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

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7 January 2021

Messenger RNA turnover in eukaryotes: pathways and enzymes

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7 January 2021

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

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7 January 2021

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

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7 January 2021

The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

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7 January 2021

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

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7 January 2021

Regulation of cap-dependent translation by eIF4E inhibitory proteins

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7 January 2021

The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

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7 January 2021

Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.

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7 January 2021

Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis

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7 January 2021

Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover

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7 January 2021

MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

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7 January 2021

HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209645

7 January 2021

AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209645

7 January 2021

Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1.

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7 January 2021

Bringing the role of mRNA decay in the control of gene expression into focus

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209645

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Dimensions Publication ID

19 September 2017

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