Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells (Q38362019)

2 September 2017

title

Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells (English)

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2 September 2017

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Qiwei Han

1

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2 September 2017

Jay Leng

2

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2 September 2017

Dafang Bian

3

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2 September 2017

Chitladda Mahanivong

4

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2 September 2017

Kevin A Carpenter

5

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2 September 2017

Zhixing K Pan

6

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2 September 2017

Jiahuai Han

7

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2 September 2017

Shuang Huang

8

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2 September 2017

language of work or name

English

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publication date

10 October 2002

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Journal of Biological Chemistry

2 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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2 September 2017

volume

277

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2 September 2017

issue

50

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2 September 2017

page(s)

48379-48385

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Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Prognostic value of urokinase plasminogen activator in primary breast carcinoma: comparison of two immunoassay methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Urokinase receptor: a molecular organizer in cellular communication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

p38 MAP kinases: beyond the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

The p38 signal transduction pathway: activation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

The p38 MAP kinase pathway and its biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Inhibition of p38 MAP kinase as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Regulated ARE-mediated mRNA decay in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

mRNA stability in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

AU-rich elements: characterization and importance in mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Transcriptional pulsing approaches for analysis of mRNA turnover in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Developmental regulation of RNA transcript destabilization by A + U-rich elements is AUF1-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-activated protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Integrin-mediated signals regulated by members of the rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Folate receptor-alpha is a cofactor for cellular entry by Marburg and Ebola viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

alpha 2 integrin subunit cytoplasmic domain-dependent cellular migration requires p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Vascular endothelial cell growth factor activates CRE-binding protein by signaling through the KDR receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Messenger-RNA-binding proteins and the messages they carry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Regulation of mRNA stability in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Alpha(v) integrin, p38 mitogen-activated protein kinase, and urokinase plasminogen activator are functionally linked in invasive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Expression and cellular localization of the urokinase-type plasminogen activator and its receptor in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Validation of immunolocalization of the urokinase receptor expression in ductal carcinoma in situ of the breast: comparison with detection by non-isotopic in-situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Mitogenic Effects of Urokinase on Melanoma Cells Are Independent of High Affinity Binding to the Urokinase Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Differential effect of Rac and Cdc42 on p38 kinase activity and cell cycle progression of nonadherent primary mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

Enhanced stability of urokinase-type plasminogen activator mRNA in metastatic breast cancer MDA-MB-231 cells and LLC-PK1 cells down-regulated for protein kinase C--correlation with cytoplasmic heterogeneous nuclear ribonucleoprotein C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

p38 mitogen-activated kinase is a bidirectional regulator of human fibroblast collagenase-1 induction by three-dimensional collagen lattices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209542200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209542200

1 reference

2 September 2017

1 reference