Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors (Q40282278)

19 September 2017

title

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors (English)

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19 September 2017

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Mitra SK

1

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19 September 2017

Mikolon D

2

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19 September 2017

Molina JE

3

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19 September 2017

Hsia DA

4

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19 September 2017

Hanson DA

5

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19 September 2017

Chi A

6

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19 September 2017

Lim ST

7

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19 September 2017

Bernard-Trifilo JA

8

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19 September 2017

Ilic D

9

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19 September 2017

Stupack DG

10

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19 September 2017

Cheresh DA

11

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19 September 2017

Schlaepfer DD

12

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19 September 2017

language of work or name

English

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publication date

8 May 2006

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19 September 2017

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19 September 2017

volume

25

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19 September 2017

issue

44

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19 September 2017

page(s)

5969-5984

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Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

A peptide corresponding to the neuropilin-1-binding site on VEGF165 induces apoptosis of neuropilin-1-expressing breast tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Breast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

VEGF-integrin interplay controls tumor growth and vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

The biology of VEGF and its receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

FAK regulates biological processes important for the pathogenesis of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Integrin signalling during tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Nontransgenic models of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Differential regulation of cell motility and invasion by FAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase is required for blood vessel morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase overexpression induces enhanced pathological retinal angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase: in command and control of cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Transcriptional regulation of the Vascular Endothelial Growth Factor gene--a concert of activating factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase: the first ten years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Multiple connections link FAK to cell motility and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Regulation of tumor angiogenesis by integrin-linked kinase (ILK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

7 January 2021

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

7 January 2021

Stimulation of angiogenesis by Ras proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

7 January 2021

Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

7 January 2021

Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209588

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209588

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Dimensions Publication ID

19 September 2017

1004394368

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1 reference