Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase (Q40284709)

19 September 2017

Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase (English)

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19 September 2017

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Zheng R

1

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19 September 2017

Iwase A

2

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19 September 2017

Shen R

3

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19 September 2017

Goodman OB Jr

4

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19 September 2017

Sugimoto N

5

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19 September 2017

Takuwa Y

6

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19 September 2017

Lerner DJ

7

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19 September 2017

Nanus DM

8

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19 September 2017

language of work or name

English

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publication date

1 May 2006

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19 September 2017

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19 September 2017

25

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19 September 2017

44

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19 September 2017

5942-5952

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209586

19 September 2017

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cites work

Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins.

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The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

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Rho and Rac take center stage

21 January 2018

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Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

21 January 2018

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Signaling by the G12 class of G proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Rho GTPases in cell biology

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

21 January 2018

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RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

21 January 2018

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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

21 January 2018

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Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.

21 January 2018

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Endothelin-1: a multifunctional molecule in cancer

21 January 2018

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Rho GTPases and the actin cytoskeleton

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Identification of a novel guanine nucleotide exchange factor for the Rho GTPase

21 January 2018

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Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB.

21 January 2018

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Direct binding of neutral endopeptidase 24.11 to ezrin/radixin/moesin (ERM) proteins competes with the interaction of CD44 with ERM proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Molecular basis for Rho GTPase signaling specificity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Tumor invasion as dysregulated cell motility

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

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Gα12 and Gα13 as key regulatory mediator in signal transduction

21 January 2018

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The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

21 January 2018

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Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

The first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Identification of G protein-coupled receptors potently stimulating migration of human transitional-cell carcinoma cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Identification of key amino acids in the gastrin-releasing peptide receptor (GRPR) responsible for high affinity binding of gastrin-releasing peptide (GRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Neuropeptides as growth factors for normal and cancerous cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

An overview of endothelin signaling in the cardiac myocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Involvement of neutral endopeptidase in neoplastic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Ribozyme- and siRNA-mediated suppression of RGS-containing RhoGEF proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

RhoA is required for monocyte tail retraction during transendothelial migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

The crossroads between cell-cell adhesion and motility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Endothelin-B receptors activate Galpha13.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Effect of prostatic neuropeptides on invasion and migration of PC-3 prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Effect of prostatic neuropeptides on migration of prostate cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Androgen-induced growth inhibition of androgen receptor expressing androgen-independent prostate cancer cells is mediated by increased levels of neutral endopeptidase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Wound-induced migration of rat hepatic stellate cells is modulated by endothelin-1 through rho-kinase-mediated alterations in the acto-myosin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209586

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209586

1 reference

Dimensions Publication ID

19 September 2017

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1 reference