The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis (Q40294317)

19 September 2017

The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis (English)

1 reference

19 September 2017

Chuanxi Cai

1

1 reference

19 September 2017

Peihui Lin

2

1 reference

19 September 2017

King-Ho Cheung

3

1 reference

19 September 2017

Na Li

4

1 reference

19 September 2017

Christina Levchook

5

1 reference

19 September 2017

Zui Pan

6

1 reference

19 September 2017

Christopher Ferrante

7

1 reference

19 September 2017

Gabrielle L Boulianne

8

1 reference

19 September 2017

J Kevin Foskett

9

1 reference

19 September 2017

David Danielpour

10

1 reference

19 September 2017

Jianjie Ma

11

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19 September 2017

language of work or name

English

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publication date

7 April 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

24

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19 September 2017

16649-16655

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Presenilin structure, function and role in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Identification of caspases that cleave presenilin-1 and presenilin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

TAT-mediated protein transduction into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Overexpression of Bax sensitizes prostate cancer cells to TGF-beta induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Inhibition of mechanosensitive cation channels inhibits myogenic differentiation by suppressing the expression of myogenic regulatory factors and caspase-3 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Unreliability of the cytochrome c-enhanced green fluorescent fusion protein as a marker of cytochrome c release in cells that overexpress Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Dysfunction of store-operated calcium channel in muscle cells lacking mg29.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Inositol 1,4,5-trisphosphate [correction of tris-phosphate] activation of inositol trisphosphate [correction of tris-phosphate] receptor Ca2+ channel by ligand tuning of Ca2+ inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

A direct optimization approach to hidden Markov modeling for single channel kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Single-channel kinetics, inactivation, and spatial distribution of inositol trisphosphate (IP3) receptors in Xenopus oocyte nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Protein transduction: unrestricted delivery into all cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512026200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512026200

1 reference

19 September 2017

1 reference